1-cyclopropanecarbonyl-1H-imidazole(CAS# 204803-26-9)
1-cyclopropanecarbonyl-1H-imidazole(CAS# 204803-26-9) Hoʻomaka
-Ke ʻano: kala ʻole a i ʻole melemele māmā
-Ka helu hoʻoheheʻe: ma kahi o 65-70 degere Celsius
-Pila paila: Ma kahi o 324 degere Celsius
-Density: approx. 1.21g/cm³
-Soluble: Soluble i ka waiʻona, dichloromethane, chloroform, hiki ʻole ke hoʻoheheʻe ʻia i ka wai
ʻO nā hoʻohana nui o kēia pūhui penei:
-he mea hoʻohana maʻamau, hiki ke hoʻohana ʻia ma ke ʻano he catalyst i ka synthesis organik. Hiki iā ia ke hana me nā aldehydes, nā ketones a me nā mea hoʻohui ʻē aʻe, a e komo i nā hopena hoʻohui, nā hopena dehydration, intramolecular cyclization reactions, etc. ma lalo o ka catalysis.
- Hiki ke hoʻohana ʻia ka hui e like me ka hoʻomākaukau ʻana i nā intermediates pharmaceutical, a loaʻa kekahi mau noi i ke kula o ka lāʻau lapaʻau.
ʻO ke ʻano maʻamau o ka hoʻomākaukau ʻana i ka calcium penei:
Ma lalo o nā kūlana maʻamau, ua hana mua ʻia ka cyclopropanone a me ka methyl iodide ma lalo o nā kūlana alkaline e hana i ka cyclopropanyl bromide e pili ana. Hoʻopili ʻia ka cyclopropanyl bromide me N-methylthiourea ma lalo o nā kūlana kumu e hana ai i ka phosphonium bromide.
E pili ana i ka ʻike palekana, he mea hoʻohuihui ia a loaʻa kekahi ʻano o ka pōʻino. Pono e mālama ʻia kēia mau mea palekana i ka wā o ka hana:
- Pono e mālama ʻia ka mea hoʻohui i loko o kahi pahu i hoʻopaʻa ʻia, ma kahi mamao o ke ahi a me nā mea oxidizing.
-I ka wā o ka lawelawe ʻana a me ka hoʻopili ʻana, pono e lawe ʻia nā hana pale pilikino e pono ai, e like me ke komo ʻana i nā mīkina lima pale kemika, nā aniani pale a me nā maka pale.
-E hōʻalo i ka hoʻopili pololei ʻana me ka ʻili a me nā maka, a pale i ka hoʻohu ʻana i ke kinoea a i ʻole ka lepo.
-i ka hoʻohana 'ana i ke kaʻina hana pono e hōʻoia i ka maikaʻi ventilation kūlana, e pale aku i ka ohi o ke kinoea i loko o ka lumi.
Eia hou, e like me nā pono a me nā kūlana o ka noi kiko'ī, e nānā i ka pepaʻikepili palekana kūpono a me nā kuhikuhi hana i ka wā e hoʻohana ai i ka hui e hōʻoia i ka palekana o ka hana.