1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
1-Phenyl-3,4-dihydroisoquinoline(CAS#52250-50-7)
ʻO 1-Phenyl-3,4-dihydroisoquinoline, helu CAS 52250-50-7, ua hōʻike i ka hiʻohiʻona kūʻokoʻa ma ke kahua o ka kemika a me ka lāʻau lapaʻau.
Mai ke kumu kemika, ua hoʻohui akamai ʻia kona mole me nā ʻāpana hoʻolālā e like me ka hui phenyl a me ke apo dihydroisoquinoline, a ʻo kēia ʻano pili atomic kikoʻī e kūkulu i kahi puʻupuʻu ao electron kūikawā, e hana ana i kāna hana kemika kūikawā a me ka paʻa. I ka nānā ʻana, hōʻike pinepine ʻia ʻo ia ma ke ʻano he paʻa me kahi ʻano crystalline, ʻo ke kala ke keʻokeʻo a i ʻole keʻokeʻo keʻokeʻo, a maʻamau a hoʻonohonoho ʻia ke ʻano aniani, kahi kūpono i ka hoʻomaʻemaʻe a me ka hoʻomaʻemaʻe ʻana ma o ka recrystallization. Ma nā ʻōlelo o ka solubility, hōʻike ia i kahi ʻano dissolution i nā mea hoʻoheheʻe kūlohelohe maʻamau e like me ka ethanol a me ka acetone, akā ʻoi aku ka haʻahaʻa o ka solubility i loko o ka wai, pili loa i ka polarity o ka mole, a hāʻawi pū i kumu no ke koho ʻana ʻōnaehana hoʻoheheʻe no ka hoʻokaʻawale ʻana a me nā hopena synthesis.
Ma nā ʻōlelo o ka lāʻau lapaʻau R&D prospects, loaʻa iā ia ka hana olaola. ʻO ke ʻano kemika o ka huahana ua like ia me kekahi o nā huahana kūlohelohe pharmacologically active, me ka manaʻo e loaʻa paha nā pahuhopu like. Hōʻike ka ʻimi mua ʻana he hopena paha ia i nā ala hōʻailona neurological, a manaʻo ʻia e komo i ka hoʻomohala ʻana i nā lāʻau lapaʻau no nā maʻi neurodegenerative, e like me ka maʻi o Alzheimer a me ka maʻi o Parkinson, ma o ka hoʻoponopono ʻana i ka hoʻoili ʻana o ka neurotransmitter abnormal a me ke kāohi ʻana i ka hyperapoptosis o nā pūnaʻi nerve. I ka manawa like, ma ke kahua o ka anti-tumor, hiki i nā pūʻulu ikaika i loko o kona hoʻolālā ke hoʻopilikia i ka hoʻonui ʻana, neʻe a me ka hoʻouka ʻana i ke kaʻina hana o nā puʻupuʻu tumora, e wehe ana i nā manaʻo hou no ka mālama ʻana i ka maʻi kanesa, ʻoiaʻiʻo, aia nō kēia i ka wā mua. ka pae o ka noiʻi keʻena hoʻokolohua, a aia nō ka nui o nā hana noiʻi e hana ʻia ma mua o ka noi ʻana.
Mai ka hiʻohiʻona o ka synthesis ʻoihana, hilinaʻi nui ʻia ke ʻano hana hoʻohui kemika organik i kēia manawa, e hoʻomaka ana mai nā mea maʻalahi maʻalahi, ma o nā hopena multi-step e kūkulu i kahi iwi molecular paʻakikī, ʻo ke kaʻina hana e pili ana i ka cyclization, substitution, condensation a me nā ʻano ʻano kūlohelohe kūlohelohe. , Ke hoʻomau nei ka poʻe noiʻi i ka hoʻonui ʻana i nā kūlana hopena, hoʻomaikaʻi i ka hua, hoʻemi i nā kumukūʻai, e hoʻokō i nā pono o ka hahai ʻana i ka noiʻi hohonu a hiki i ka nui-nui. hana ʻana. Me ka hoʻohui ʻana o nā ʻenehana i nā ʻano ʻano like ʻole, ʻo ka hoʻomohala holoʻokoʻa o 1-Phenyl-3,4-dihydroisoquinoline e manaʻo ʻia e wikiwiki, e hoʻokomo i ka impetus hou i ke olakino kanaka a me ka holomua ʻepekema a me ka ʻenehana.
