1H-Pyrazole-3-carboxylicacid 5-methyl-（CAS# 696-22-0)
| Nā hōʻailona pōʻino | Xi – Hoʻohaunaele |
| Nā Code Risk | R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. |
| Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S37/39 – E hoʻohana i nā mīkina lima kūpono a me ka pale maka/maka |
Hoʻolauna
ʻO ia ka mea hoʻohuihui olaola me ke ʻano kemika C5H5N2O2. ʻO ka maʻamau he ʻeleʻele ʻole a i ʻole melemele ʻeleʻele paʻa.
ʻElua mau pūʻulu hana o ka hui, ʻo kekahi he apo pyrazole a ʻo kekahi he hui hana carboxylic acid. Hiki ke hoʻoheheʻe ʻia a hiki ke hoʻoheheʻe ʻia i ka wai a me nā mea hoʻoheheʻe kūlohelohe maʻamau. ʻO ka hui methyl i loko o kona ʻano hana hydrophobic.
Ma ke ʻano he hui heterocyclic, 5-methyl-he mau ʻano hana olaola. Hoʻohana nui ʻia ia i ka noiʻi lāʻau lapaʻau a me ka synthesis lāʻau lapaʻau, pinepine ma ke ʻano he kumu a i ʻole waena. Hoʻopili ʻia nā noi kikoʻī i ka synthesis o nā analogs vitamin B1, insecticides, plavix inhibitors (kahi pūhui i hoʻohana ʻia e kāohi i ka ulu ʻana o nā mea kanu), a me nā mea like.
Hoʻomākaukau, hiki ke loaʻa ka 5-methyl-ma ka hana ʻana i ka atom nitrogen o ke apo pyrazole me kahi mea methylating (e laʻa me methyl iodide). Lawe ʻia kēia ʻano hana e ka hopena N-methylation, ʻo ke ʻano maʻamau ka hopena o ka nucleophile pili me kahi N-methyl reagent.
