![1H-Pyrrolo[2 3-b]pyridine 6-methoxy-（CAS# 896722-53-5)](https://cdn.globalso.com/xinchem/1HPyrrolo23bpyridine6methoxy.png)
1H-Pyrrolo[2 3-b]pyridine 6-methoxy-（CAS# 896722-53-5)
| Nā hōʻailona pōʻino | Xn – Poino |
| Nā Code Risk | R22 – Poino ke aleia R36 – He mea hoʻonāukiuki i nā maka |
| Ka wehewehe palekana | 26 - Inā pili me nā maka, holoi koke me ka wai nui a ʻimi i ka ʻōlelo aʻoaʻo olakino. |
| WGK Kelemānia | 3 |
| Papa Hazard | HOOLAHA |
Hoʻolauna
ʻO ka 6-methoxy-1H-cryrolo [2,3-b]pyridine he hui lāʻau me ke ʻano kemika C9H8N2O. Penei kona mau waiwai.
1. Nani: 6-methoxy-1H-chrrolo [2,3-b] pyridine he kala ʻole i ke aniani melemele.
2. wahi hehee: e pili ana i 105-108 ℃.
3. Kohu paila: ma kahi o 325 ℃.
4. Solubility: Hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe kūlohelohe e like me chloroform, methanol a me dimethyl sulfoxide, a hiki ke hoʻoheheʻe iki ʻia i ka wai.
He mea nui ka 6-methoxy-1H-yrrolo [2,3-b]pyridine i ka noiʻi lāʻau lapaʻau a me ke kemika, penei:
1. Ka lāʻau lapaʻau: Hoʻohana nui ia i ka noiʻi a me ka hoʻomohala ʻana i ka anti-tumor, anti-inflammatory, anti-cancer a me nā lāʻau lapaʻau ʻē aʻe.
2. Hoʻohui kemika: Ma ke ʻano he koʻikoʻi koʻikoʻi i ka synthesis organik, hiki ke hoʻohana ʻia no ke kūkulu ʻana i nā hale molekala organik paʻakikī.
ʻO nā ʻano hana no ka hoʻomākaukau ʻana i ka 6-methoxy-1H-cryrolo [2,3-b] pyridine ka mea nui penei:
1. N-methylation reaction of indole: Hoʻopili ʻia ʻo Indole me ka methyl halide e hoʻohua ai i ka 6-methyl indole, a laila hana ʻia me ka N-methyl vinyl amine e hoʻohua i ka 6-methoxy-1H-cryrolo [2,3-b] pyridine.
2. Redox reaction of indole: 6-methoxy-1H-pyridolo [2,3-b]pyridine hiki ke loaʻa ma ka reacting indole me ka sodium nitrite a me tert-butyl peroxide.
E pili ana i ka ʻike palekana, he liʻiliʻi nā haʻawina e pili ana i ka ʻona a me ka pōʻino o 6-methoxy-1H-pyridolo [2,3-b] pyridine, no laila pono ka loiloi palekana kikoʻī e noiʻi hou aku. I ka hana ʻana i nā hoʻokolohua a i ʻole nā noiʻi, pono e hahai i nā hana hoʻokolohua a me nā hana palekana, e pale i ka hoʻopili pololei ʻana me ka ʻili a me nā maka, e hoʻolohe i nā mea pale, a pale i ka inha ʻana i nā aerosol a i ʻole ka lepo. Inā pono, pono e hoʻohana ʻia ma kahi wahi i hoʻoluʻu maikaʻi ʻia.
