2-Amino-6-bromopyridine(CAS# 19798-81-3)
Pilikia a palekana
Nā Code Risk | R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. |
Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S36 – E komo i nā lole pale kūpono. S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. |
WGK Kelemānia | 3 |
HS Code | 29333999 |
Papa Hazard | HOOLAHA |
2-Amino-6-bromopyridine(CAS# 19798-81-3) ʻIkepili
Nānā nui | ʻO 2-amino i hoʻololi ʻia i ka nitrogen-i loko o nā pūhui heterocyclic ʻeono mau lālā he mau noi nui i ka ʻoihana kemika, e like me 2-amino -6-Bromopyridine kekahi o nā hale koʻikoʻi i nā lāʻau lapaʻau synthetic a me nā molekole kemika mahiʻai, a hoʻohana nui ʻia i ka synthesis. nā huahana kūlohelohe, nā lāʻau lapaʻau, nā mea luminescent a me nā kemika maikaʻi like ʻole. |
Palapala noi | ʻO 2-amino i hoʻololi ʻia i ka nitrogen i loaʻa i nā pūhui heterocyclic ʻeono i hoʻohana nui ʻia i ka ʻoihana kemika, e like me 2-amino -6-Bromopyridine kekahi o nā hale koʻikoʻi i nā lāʻau lapaʻau synthetic a me nā molekole kemika mahiʻai, a hoʻohana nui ʻia i ka synthesis. nā huahana kūlohelohe, nā lāʻau lapaʻau, nā mea luminescent a me nā kemika maikaʻi like ʻole. |
Hoʻomākaukau | Hoʻomākaukau i ka 2-amino-6-bromopyridine: E hoʻohui i ka 2-fluoro-6-bromo-pyridine (1mmol), pentamidine hydrochloride (2mmol), sodium tert-butoxide (3mmol), HO (0.5mL) a me diethylene glycol dimethyl ether (2.5). mL) i loko o kahi paipu hopena 25 ml. Ua lawe ʻia ka hopena ma 150 ℃ no 24 mau hola. Ma hope o ka pau ʻana o ka hopena, ua hoʻomaha ʻia i ka lumi wela. E hoʻohui i 10mL o ka ethyl acetate e kinai i ka hopena, e hoʻohui i 6mL o ka wai paʻakai kuʻuna e holoi, e hoʻokaʻawale i ka māhele organik, a laila e unuhi i ka māhele wai me ka ethyl acetate no 3 mau manawa (ʻo ka nui o ka ethyl acetate i kēlā me kēia manawa he 6mL) a hoʻohui i ka organik. ʻāpana, e hoʻohui i ka sodium sulfate anhydrous e maloʻo, e wehe i ka mea hoʻoheheʻe me ka mea hoʻoheheʻe organik a me ka mea hoʻoheheʻe inorganic ma ka hoʻoheheʻe ʻana i ka momi, a laila e hoʻokaʻawale i ka mea hoʻoheheʻe organik e ka chromatography kolamu e loaʻa ai ka huahana i manaʻo ʻia 2-amino-6-bromopyridine me ka 93%. |
hoʻohana | lāʻau waena. no ka hana pono o 7-azafindole i loko o ka ipu hoʻokahi; no ka hana ʻana i nā lāʻau anti-HIV |
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