2-Bromo-5-(trifluoromethyl)pyridine（CAS# 50488-42-1)
| Nā Code Risk | R25 - He mea ʻawaʻawa inā ʻai ʻia R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. |
| Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. S22 – Mai hanu i ka lepo. S36 – E komo i nā lole pale kūpono. |
| UN ID | UN 2811 6.1/PG 3 |
| WGK Kelemānia | 3 |
| HS Code | 29333990 |
| Papa Hazard | HOOLAHA |
| Hui Pūʻulu | Ⅲ |
Hoʻolauna
ʻO 2-Bromo-5-(trifluoromethyl)pyridine (ʻike pū ʻia ʻo BTFP) he mea hoʻohuihui. ʻO kēia ka hoʻolauna ʻana i kona ʻano, hoʻohana, ʻano hoʻomākaukau a me ka ʻike palekana:
ʻAno maikaʻi:
- Ke ʻano: Paʻa keʻokeʻo
- Kaumaha Molekala: 206.00 g/mol
- Hiki ke hoʻoheheʻe ʻia: hiki ke hoʻoheheʻe ʻia ka BTFP i loko o nā mea hoʻoheheʻe organik (e laʻa, nā ʻawaʻawa, ethers, ketones) akā ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai.
E hoʻohana:
- Ma ke ʻano he synthesis intermediate: Hoʻohana nui ʻia ʻo BTFP i ka hoʻomākaukau ʻana i nā intermediates synthesis organik, e like me nā pūhui pyridine, nā mea ʻala, etc.
- Ma ke ʻano he ligand: Hiki ke hoʻohana ʻia ʻo BTFP ma ke ʻano he ligand no nā paʻakikī metala a komo i nā ʻano catalytic reactions a me ka hoʻomākaukau ʻana i nā mea hana.
- Ma ke ʻano he reagent: He kuleana koʻikoʻi ka BTFP i ka synthesis organik, e like me ka hoʻohui ʻana, ka hoʻololi ʻana, a me ka hopena hoʻemi.
Hanana:
Hiki ke hoʻohui ʻia ʻo 2-Bromo-5-(trifluoromethyl)pyridine e nā pae aʻe:
1. E hoʻoheheʻe i ka 2-amino-5-(trifluoromethyl)pyridine i loko o kahi mea hoʻoheheʻe kūlohelohe kūpono, e like me ka waiʻona a i ʻole ketone.
2. E hoʻohui i nā pūhui bromine (eg hydrogen bromide, methyl bromide).
3. Hana i ka hopena ma ka wela kūpono a me ka hoʻoulu ʻana.
4. E kānana i ka huahana a hoʻokō i ka crystallization a me ka hoʻomaʻemaʻe.
ʻIke palekana:
- Hiki i ka BTFP ke hoʻopaʻa a hoʻoheheʻe paha i nā wela haʻahaʻa, e ʻoluʻolu e mālama i ka lumi wela a pale i ka crystallization.
- E hoʻohana i nā mīkina lima pale kūpono a me nā aniani i ka wā o ka hana e pale aku i ka pili ʻana me ka ʻili a me nā maka.
- Hōʻalo i ka hanu ʻana i kona lepo a i ʻole ka mahu, no ka mea, he hopena hoʻonāukiuki paha ka BTFP ma ka ʻōpū hanu.
- E nānā i ka manual palekana pili i ka wā e hoʻohana ai a e lawelawe ana i ka BTFP, a e hoʻolei i nā ʻōpala a me nā mea hoʻoheheʻe kūpono.
