2-Chloro-3-fluoro-6-picoline（CAS# 374633-32-6)

Hoʻolauna

ʻAno: ʻAʻole waihoʻoluʻu i ka wai melemele māmā, ʻo kēia hiʻohiʻona hiʻohiʻona e pili ana i ka māmā a me ka wela, a pono e hana i nā mea e pale aku ai i ka mālamalama a me ka mahana i ka wā o ka mālama ʻana a me ka lawe ʻana, e like me ka hoʻohana ʻana i nā hue aniani brown a mālama iā lākou. i loko o kahi hale kūʻai ʻoluʻolu e pale aku i ka hohonu a me ka pōʻino o ka kala.

Solubility: ʻO ka hui he mea hiki ke hoʻoheheʻe maikaʻi ʻia i nā mea hoʻoheheʻe kūlohelohe maʻamau, e like me toluene a me dichloromethane, e hahai ana i ke kumu o ka solubility like, a he pilina me nā mea hoʻoheheʻe organik ma muli o ka ʻāpana hydrophobic o ka mole; Eia naʻe, haʻahaʻa ka solubility i loko o ka wai, a ʻo ka hoʻopaʻa ʻana o ka hydrogen ikaika ma waena o nā molekele wai he paʻakikī ke wāwahi pono ʻia e ka mole, e paʻakikī ke hoʻopuehu.
ʻO ka helu paila a me ka nui: pili pili loa ka ʻikepili helu paila i kona volatility a hiki ke hāʻawi i nā ʻāpana koʻikoʻi no nā hana e like me ka distillation a me ka hoʻomaʻemaʻe ʻana, akā naʻe, ʻaʻole i hōʻike nui ʻia ke kumukūʻai paila kikoʻī. ʻOi aku ka kiʻekiʻe o kona mānoanoa ma mua o ka wai, a ʻo ka hoʻomaopopo ʻana i ka haʻahaʻa hiki ke kōkua i ke koho pololei ʻana i ka pilina hoʻololi nui-nui ma nā hana hoʻokolohua a i ʻole kaʻina hana ʻoihana e like me ka hoʻoili wai a me ke ana pololei.
Nā waiwai kemika
Pane hoʻololi: ʻO ka chlorine atom a me ka fluorine atom i loko o ka mole ka pae hoʻonā. I ka hopena o ka nucleophilic substitution, hiki i nā nucleophiles ikaika ke hoʻouka i nā wahi i loaʻa ai nā ʻātoma chlorine a me fluorine, hoʻololi i nā ʻātoma pili, a hana i nā derivatives pyridine hou. No ka laʻana, ua hui pū ʻia me kekahi mau nucleophiles i loko o ka nitrogen a me ka sulfur no ka hoʻomohala ʻana i nā pūhui heterocyclic paʻa i ka nitrogen me nā hale paʻakikī no ka ʻike ʻana i ka lāʻau a i ʻole ka synthesis waiwai.
ʻO ka hopena Redox: ʻo ke apo pyridine ponoʻī he paʻa paʻa, akā i ka wā e hui pū ʻia ai nā oxidants ikaika, e like me ka potassium permanganate a me ka hydrogen peroxide me nā kūlana acidic, hiki ke hoʻomake ʻia, e hopena i ka luku ʻana a i ʻole ka hoʻololi ʻana i ke ʻano o ke apo pyridine; ʻO ka mea ʻē aʻe, me kahi mea hoʻohaʻahaʻa kūpono, e like me nā hydride metala, hiki ke hiki i ka hydrogenation o nā paʻa unsaturated intramolecular.
ʻO ka hā, ke ʻano hana synthesis
ʻO ke ala synthesis maʻamau, ʻo ia ka hoʻomaka ʻana mai nā derivatives pyridine maʻalahi a kūkulu mālie i ka hoʻolālā pahuhopu ma o ka halogenation a me ka fluorination reactions. ʻO nā pūhui pyridine mea hoʻomaka e koho mua ʻia a hoʻokomo ʻia nā pūʻulu methyl i ka manawa like; A laila e hoʻohana i nā mea hoʻoheheʻe halogenation, e like me ka chlorine a me ka chlorine wai, me nā catalysts kūpono a me nā kūlana hopena, e hoʻokō i ka hoʻokomo ʻana i nā ʻātoma chlorine; ʻO ka mea hope loa, ua hoʻohana ʻia nā reagents fluorinated, e like me Selectfluor, no ka fluorinate pololei i ka pae i loaʻa i ka 2-chloro-3-fluoro-6-methylpyridine.
Hoʻohana
ʻO ka hui ʻana o ka lāʻau lapaʻau: aloha ʻia kona ʻano kūʻokoʻa e nā mea lapaʻau lāʻau lapaʻau, a he kūlana kiʻekiʻe ia no ka hoʻomohala ʻana i nā lāʻau antibacterial, antiviral, a me antitumor hou. ʻO nā waiwai uila a me ka hoʻolālā spatial o nā apo pyridine a me kā lākou mau mea pani e hiki ke hoʻopaʻa pono i nā protein i hoʻopaʻa ʻia i loko o vivo, a manaʻo ʻia e hoʻololi ʻia i mau mea hana me ka maikaʻi maikaʻi loa ma hope o ka hoʻololi ʻana i nā pae he nui.
ʻepekema Materials: Ma ke kahua o ka organik material synthesis, hiki ke hoʻohana ʻia e hana i nā mea polymer functional, fluorescent material, etc., ma muli o kona hiki ke hoʻokomo pololei i ka chlorine, fluorine atoms a me nā hale pyridine, e hāʻawi i nā mea me ka uila kūikawā a me ka optical. nā waiwai, a paipai i ka hoʻomohala ʻana i nā ʻenehana ʻokiʻoki e like me nā mea akamai a me nā mea hōʻike.