2-Cyano-4-methylpyridine（CAS# 1620-76-4)
Pilikia a palekana
| Nā hōʻailona pōʻino | Xi – Hoʻohaunaele |
| Nā Code Risk | R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. R41 – Ka pilikia o ka poino nui i na maka R37/38 – Hoʻonanea i ka ʻōnaehana hanu a me ka ʻili. R22 – Poino ke aleia R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. |
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S36/37 – E hoʻohana i nā lole pale kūpono a me nā mīkina lima. S39 - Hoʻohana i ka pale maka / maka. S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S36 – E komo i nā lole pale kūpono. |
| UN ID | 3276 |
| WGK Kelemānia | 3 |
| HS Code | 29333990 |
| Papa Hazard | 6.1 |
| Hui Pūʻulu | III |
2-Cyano-4-methylpyridine（CAS# 1620-76-4) ʻIkepili
| Palapala noi | ʻO ka 2-cyano-4-methylpyridine he mea koʻikoʻi waena, hiki ke hoʻokahe mua ʻia mai ka 4-methylpyridine e hoʻomākaukau ai i ka 4-Methyl-pyridine-N-oxide, a laila hoʻololi ʻia me ka hui cyano e loaʻa ai. Hiki ke hoʻohana ʻia ka 4-methyl-pyridine-N-oxide e hoʻomākaukau ai i ka 4-methyl -2, 6-dicarboxypyridine, 4-methyl -2, 6-dicarboxypyridine he pyridine derivative maikaʻi loa a me kahi hui waena koʻikoʻi, i hoʻohana nui ʻia. ma ke kahua o ka laau lapaau. |
| hoomakaukau ana | 4-methyl-pyridine-N-oxide (0.109g,1mmol), trimethylcyanosilane (0.119g,1.2mmol), H-diethyl phosphite (0.276g,2mmol), carbon tetrachloride (0.308g,2mmol), triethylamine (0.202g, 2mmol) a me ka acetonitrile 10mL i kahi 50mL ʻekolu-waha pahu, hoʻopā i ka lumi wela no 6h. Ma hope o ka pau ʻana o ka hopena, hoʻoneʻe ʻia ka mea hoʻoheheʻe ma lalo o ke kaomi hoʻemi ʻia a hoʻokaʻawale ʻia e ke kolamu chromatography (petroleum ether/ethyl acetate, V/V = 4:1) no ka loaʻa ʻana o ka pūhui pahu wai kala ʻole me 80% yield. |
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