2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE(CAS#32531-66-1)
2-(DIPHENYLMETHYL)-QUINUCLIDIN-3-ONE, CAS NUMERO 32531-66-1, HE NUI NA MEA HOPE MA KE KEMIA A ME NA PONO PILI.
Mai ka nānā ʻana o ka hoʻolālā kemika, hoʻohui kona ʻano molekala kūikawā i nā ʻāpana o ka diphenyl methyl a me ka quinine. Diphenyl methyl pūʻulu lawe mai i ka nui steric hindrance a me ka conjugation nenoaiu, e pili ana i ka electron ao kahe o ka mole, oiai ka quinine cyclic ketone hapa haawi i ka mole i kekahi mau 'ano paakiki a me ke kumu, a me na mea elua synergistically kūkulu i ka 'ano paʻa akā reactive kemika. ʻO ka mea maʻamau i ke ʻano o ka pauka crystalline keʻokeʻo, hoʻomaʻamaʻa kēia ʻano paʻa i ka mālama ʻana, ka lawe ʻana, a me ka hoʻoili ʻana ma hope. Ma nā ʻōlelo o ka solubility, he mea hiki ke hoʻoheheʻe maikaʻi ʻia i nā mea hoʻoheheʻe ʻole polar e like me benzene a me toluene, ʻo ia ka mea ma muli o ka ʻāina non-polar o ka mole, ʻoiai ʻaʻole hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe polar e like me ka wai a me nā waiʻona. He mea koʻikoʻi loa ia no ke koho ʻana i ka solvent, ka hoʻokaʻawale ʻana a me ka hoʻomaʻemaʻe ʻana i ka synthesis kemika.
Ma ke ʻano o ka hiki ke hoʻohana i ka lāʻau lapaʻau, ua like kona ʻano me kekahi o nā lāʻau lapaʻau psychotropic i loaʻa, e manaʻo ana e hana paha ia i nā pahuhopu pili i ke kikowaena. Ua hōʻike ʻia nā haʻawina mua he hopena hoʻoponopono i ka uptake a me ka hoʻokuʻu ʻana o nā neurotransmitters, a ua manaʻo ʻia e hoʻohana ʻia i ka mālama ʻana i nā maʻi psychiatric e like me schizophrenia a me ke kaumaha, a hoʻomaikaʻi i nā hōʻailona o nā mea maʻi ma ke komo ʻana i ka hōʻailona aʻalolo. Eia nō naʻe, i kēia manawa, aia ka hapa nui o lākou i ke kahua o nā hoʻokolohua cell a me ka ʻimi hoʻohālike holoholona, a aia nō kahi lōʻihi e hele ai ma mua o ka lilo ʻana i mau lāʻau lapaʻau, a he mea pono e ʻimi hohonu i kā lākou mau hana pharmacological, nā hopena ʻino, pharmacokinetics a me nā mea ʻē aʻe he nui.
Mai ka hiʻohiʻona o ke kaʻina hana synthesis, hilinaʻi nui ia i ke ala synthesis maikaʻi. E hoʻomaka ana me ka maʻalahi a maʻalahi ka loaʻa ʻana o nā mea maka, ua kūkulu ʻia ka molekele i hoʻopaʻa ʻia ma o nā ʻanuʻu hopena paʻakikī e like me ka cyclization, substitution, a me ka hui ʻana. Ke ho'āʻo mau nei nā mea noiʻi i nā catalysts hou a me nā media pane, e hoʻonui ana i ka mahana o ka hopena, ka manawa a me nā kūlana ʻē aʻe, a me ka hoʻoikaika ʻana e hoʻomaikaʻi i ka hana synthesis a hoʻemi i nā kumukūʻai, i mea e hōʻoia ai i ka hiki ke hahai i ka noiʻi hohonu a me ka hana ʻoihana.