(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone(CAS#17092-92-1)

(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone(CAS#17092-92-1)

1. ʻIke Kumu
Inoa: (2,6,6-Trimethyl-2-hydroxycyclohexylidene) acetic acid lactone.
Helu CAS:17092-92-1, ʻo ia ka helu ʻike kūʻokoʻa o ka pūhui i loko o ka ʻōnaehana hoʻopaʻa inoa kemika, kahi kūpono no ka nīnau pololei a me ka loaʻa ʻana o ka ʻikepili ma ka honua holoʻokoʻa.
ʻO ka lua, nā hiʻohiʻona kūkulu
Loaʻa i kona ʻano molekala kahi hui cyclohexyl ʻeono me kahi hui hydroxyl i hoʻopili ʻia i ke kūlana 2, a me kahi trimethyl substituent ma kēia kūlana, e hāʻawi ana i ka mole i kekahi mea steric hindrance a me nā waiwai uila. Aia kekahi ʻano lactone i hoʻokumu ʻia e ka hui methylene a me ka hui carbonyl i loko o ka mole, aia kekahi paʻa a he hopena koʻikoʻi i ka hana kemika, solubility a me nā waiwai kino a me nā mea kemika o ka pūhui.
3. Na waiwai kino
ʻAno: ʻO ka maʻamau keʻokeʻo i ka pauka crystalline melemele māmā a paʻa paha, kūlana paʻa, maʻalahi ke mālama a mālama.
Solubility: Loaʻa iā ia kekahi solubility i nā mea hoʻoheheʻe kūlohelohe maʻamau e like me ka ethanol, ether, chloroform, a me nā mea ʻē aʻe, a hiki ke hana i kahi hopena kūlike no nā hopena kemika ma hope a i ʻole nā ​​hoʻāʻo analytical; ʻAʻole hiki ke hoʻoheheʻe ʻia i loko o ka wai a hahai i ke kumu o ka "dissolvability like", e hōʻike ana i kona ʻano molekole non-polar.
Heheʻe wahi: He mea paʻa paʻa helu hehee ai, oia kekahi o na mea nui o ka hoʻomaʻemaʻe 'ike, a me ka maemae o ka hāpana hiki ke preliminarily hookolokolo ma ka pololei hoʻoholo 'ana i ka helu heheʻe, a me ka kiko'ī helu hehee ai waiwai hiki ke kūkākūkā ma. nā palapala kemika ʻoihana a i ʻole ka ʻikepili.
ʻO ka hā, nā waiwai kemika
Loaʻa iā ia ke apo maʻamau o ka lactone, a ma lalo o nā kūlana catalytic o ka waika a me ka alkali, hiki ke haki ke apo lactone, a hana ia me nā nucleophiles a me nā electrophiles e hoʻohua i nā ʻano derivatives, e hāʻawi ana i nā ʻano like ʻole. nā ala no ka synthesis organik.
Ma ke ʻano he pūʻulu hana ikaika, hiki i ka hui hydroxyl ke komo i ka esterification, etherification a me nā hopena ʻē aʻe e hoʻololi hou i ke ʻano o ka molekala a hoʻonui i kāna ʻano noi, e like me ka hoʻomākaukau ʻana i nā pūhui ester me ka hana biological kūikawā no ka noiʻi lāʻau a me ka hoʻomohala ʻana.
5. Keʻano hana hoʻohui
ʻO kahi ala synthetic maʻamau, ʻo ia ka hoʻohana ʻana i nā cyclohexanone derivatives me nā mea hoʻololi kūpono e like me ka mea hoʻomaka, a kūkulu i ka hoʻolālā molecular target ma o nā hopena he nui. No ka laʻana, hoʻokomo ʻia nā pūʻulu trimethyl ma o ka hopena alkylation, a laila kūkulu ʻia nā apo lactone a me nā pūʻulu hydroxyl e ka oxidation a me ka cyclization, a ʻo nā ʻano hopena e like me ka mahana, pH, ka manawa pane, etc. ka hua nui a me ka maemae.
ʻO ke ono, ke kahua o ka noi
ʻOihana ʻala: ma muli o kona ʻano kū hoʻokahi e lawe mai i kahi ʻala kūikawā, hiki ke hoʻohana ʻia i mea ʻono i loko o nā mea ʻala, nā mea hoʻonaninani, nā mea ʻala meaʻai, a me nā mea ʻē aʻe, ma hope o ka dilution a me ka hui ʻana, e hoʻohui i kahi ʻono kūʻokoʻa.
Kahua lāʻau lapaʻau: Ma ke ʻano he waena o ka hoʻohui ʻana i ka lāʻau lapaʻau, hiki ke hoʻokomo ʻia kāna mau ʻāpana i loko o nā mole me ka hana pharmacological e hoʻololi i ka hana, hoʻomaikaʻi i nā waiwai pharmacokinetic, a kōkua i ka noiʻi a me ka hoʻomohala ʻana i nā lāʻau hou, i manaʻo ʻia e hoʻohana ʻia no ka mālama ʻana i kahi nā ʻano maʻi like ʻole.
Organic synthesis: Ma ke ʻano he kī hale kiʻekiʻe, komo ia i ke kūkulu ʻana i ka huina o ka synthesis o nā huahana kūlohelohe paʻakikī a me ka hoʻomākaukau ʻana i nā mea hana organik hou, hoʻoikaika i ka hoʻomohala ʻana o ke kahua o ka kemika organik, a hāʻawi i kumu no ka hana ʻana i nā mea hou. mea waiwai.