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3-[(3-amino-4-methylamino-benzoyl)pyridin-2-yl-amino]-(CAS# 212322-56-0)

Waiwai Kemika:

ʻĀpana Molekala C18H22N4O3
Molar Mass 342.4
ʻO ka mānoanoa 1.261±0.06 g/cm3(Wanamua)
Lae hehee 104.0 a i 108.0 °C
Lae Boling 576.2±50.0 °C(Wānana ʻia)
Lae Flash 302.248°C
Ka hoʻoheheʻe DMSO (Lili iki), Methanol (Lili iki)
Puʻupuʻu mahu 0mmHg ma 25°C
Ka nana aku Paʻa
kala kala Keʻokeʻo-keʻokeʻo a Pale Beige
pKa 5.37±0.11(Wānana ʻia)
Kūlana Waihona ma lalo o ke kinoea inert (nitrogen a i ʻole Argon) ma 2-8 °C
Hōʻike Hōʻike 1.64

Huahana Huahana

Huahana Huahana

 

Hoʻolauna

ʻO N-[4-methylamino-3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, i hoʻopaʻa pinepine ʻia ʻo AAPB, he hui kemika. ʻO kēia ka hoʻolauna ʻana i ke ʻano, hoʻohana, hana hana a me ka ʻike palekana o AAPB:

 

ʻAno maikaʻi:

- Ke ʻano: ʻO ka maʻamau keʻokeʻo a i ka māmā melemele crystalline paʻa.

- Solubility: Hiki ke hoʻoheheʻe ʻia e like me ka dimethyl sulfoxide a me ka methylene chloride, hiki ʻole ke hoʻoheheʻe ʻia i ka wai.

- Kemimi: AAPB ua hydrolyzed ma lalo o ka waikawa a hiki ke hana me nā amine a me nā aldehydes aromatic a me nā ketones.

 

E hoʻohana:

Hoʻohana pinepine ʻia ʻo AAPB ma ke ʻano he waena i ka synthesis organik a hiki ke hoʻohana ʻia e hoʻomākaukau i nā pūhui i loaʻa nā pyridine a i ʻole benzamide.

 

Hanana:

ʻO ke ʻano o ka hoʻomākaukau ʻana o AAPB he paʻakikī a maʻamau e pili ana i kahi pane he nui. ʻO ke ala synthetic maʻamau e pili ana i ka hopena o nā mea maka e like me ka pyridone a me ka ethyl para-aminobenzoate, i hana ʻia ma o nā ʻanuʻu.

 

ʻIke Palekana: Ma ke ʻano he mea hoʻohuihui, loaʻa paha nā hopena ʻona i ke kanaka a pono e lawe ʻia nā ʻano palekana o ka hale hoʻokolohua kūpono, e like me ke komo ʻana i nā mea pale a me ka hana ʻana ma lalo o nā kūlana hale hoʻoheheʻe maikaʻi. Pono nō hoʻi e pale i ka pilina me nā oxidants a me nā waikawa ikaika.


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