3-Bromo-5-fluoropyridine（CAS# 407-20-5)
| Nā Code Risk | R22 – Poino ke aleia R37/38 – Hoʻonanea i ka ʻōnaehana hanu a me ka ʻili. R41 – Ka pilikia o ka poino nui i na maka R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. R10 – Hiki ke ahi |
| Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S39 - Hoʻohana i ka pale maka / maka. S36 – E komo i nā lole pale kūpono. S16 – E hoʻokaʻawale i nā kumu hoʻā. |
| UN ID | UN2811 |
| WGK Kelemānia | 3 |
| HS Code | 29333990 |
| Nānā Hazard | Hoʻonanea |
| Papa Hazard | 6.1 |
Hoʻolauna
ʻO 5-Bromo-3-fluoropyridine kahi mea hoʻohui. ʻO kēia ka hoʻolauna ʻana i kona ʻano, hoʻohana, ʻano hoʻomākaukau a me ka ʻike palekana:
ʻAno maikaʻi:
- 5-Bromo-3-fluoropyridine he paʻa me ka morphology o nā keʻokeʻo keʻokeʻo a melemele paha.
- He hui organohalogen me ka hana kemika kiʻekiʻe.
- 5-Bromo-3-fluoropyridine ʻaʻole hiki ke hoʻoheheʻe ʻia i loko o ka wai ma ka lumi wela, akā hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe kūlohelohe e like me ka ethanol a me nā ethers.
E hoʻohana:
- Hoʻohana pinepine ʻia ʻo 5-Bromo-3-fluoropyridine ma ke ʻano he reagent koʻikoʻi i ka synthesis organik.
- Loaʻa iā ia ka hoʻololi electrophilic ikaika a me ka hoʻoulu ʻana, a hiki ke hoʻohana ʻia no ka hoʻololi ʻana, ka hui ʻana a me nā hopena cyclization i nā hopena synthesis organik.
Hanana:
- 5-Bromo-3-fluoropyridine hiki ke synthesized e nā ʻano like ʻole, ʻo ke ʻano maʻamau ka hana ʻana i ka bromofluoropyridine me ka acetonitrile.
- Hiki ke loaʻa ka 3-Bromopyridine ma ka hana mua ʻana me ka lithium subbromide e hana ai i ka 3-bromopyridine, a laila e hana me ka sodium fluoride e loaʻa ai ka 5-bromo-3-fluoropyridine.
ʻIke palekana:
- ʻO 5-Bromo-3-fluoropyridine he mea hoʻohuihui kino i mea pōʻino a pono e mālama pono ʻia i loko o ka hale hana.
- He hopena hoʻonāukiuki paha ia ma nā maka a me ka ʻili a pono e pale ʻia ka pilina pololei.
- Pono e mālama ʻia ʻo 5-Bromo-3-fluoropyridine i loko o kahi pahu hau, ma kahi mamao o ke ahi a me nā wela kiʻekiʻe.
- I ka hoʻohana ʻana a me ka lawelawe ʻana, e hahai i nā kaʻina hana palekana kūpono a hoʻolako ʻia me nā mea pale kūpono e like me nā mīkina lima a me nā maka.
