ʻaoʻao_banner

huahana

4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile(CAS# 189956-45-4)

Waiwai Kemika:

ʻĀpana Molekala C11H8N4O
Molar Mass 212.21
ʻO ka mānoanoa 1.31±0.1 g/cm3(Wanamua)
Lae hehee >300°C
Lae Boling 399.7°C ma 760 mmHg
Lae Flash 195.6°C
Ka hoʻoheheʻe DMSO (Lili iki), Methanol (Lili iki)
Puʻupuʻu mahu 0-0Pa ma 20-25 ℃
Ka nana aku Paʻa
kala kala Pale Brown a Palaunu
pKa 8.66±0.40(Wānana ʻia)
Kūlana Waihona 2-8°C
Hōʻike Hōʻike 1.67

Huahana Huahana

Huahana Huahana

4-[(4-Hydroxy-2-pyrimidinyl)amino]benzonitrile(CAS#189956-45-4) ʻIkepili

LogP 0.9 ma ka pH6.6
hoʻohana 4- [(4-hydroxy-2-pyrimidinyl) amino] benzonitrile hiki ke hoʻohana ʻia ma ke ʻano he waena i ka synthesis organik a me ka intermediate pharmaceutical, a hiki ke hoʻohana ʻia i loko o ke kaʻina hana hoʻomohala Organic a me ka noiʻi a me ka hoʻomohala lāʻau.
hoomakaukau ana kaupaona 2-(methylthio) pyrimidine -4(3H)-hoʻokahi (3g,21mmol) a me 4-aminobenzonitrile (2.99g,25mmol) i loko o ka ipu 50mL poʻe lalo, pale ʻia e ka nitrogen, hoʻomehana mālie ʻia i 180 ℃, a hana ʻia no 8 hola. Ma hope o ka maʻalili ʻana o ka hopena, hoʻohui ʻia ka 20mL o ka acetonitrile no ka mālama ultrasonic, kānana, holoi ʻia ka keke kānana me ka acetonitrile, ʻaʻohe 4-aminobenzonitrile koena i ʻike ʻia e TLC, a ʻo ka paʻa melemele māmā i loaʻa ma ka hoʻomaloʻo ʻana i ka keke kānana he 4-( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile me ka hua o 73.6%.

  • Mua:
  • Aʻe:

  • E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou