5-Fluorouracil（CAS# 51-21-8)
| Nā Code Risk | R22 – Poino ke aleia R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. R52 – He pōʻino i nā mea ola wai R25 - He mea ʻawaʻawa inā ʻai ʻia |
| Ka wehewehe palekana | S36 – E komo i nā lole pale kūpono. S36/37 – E hoʻohana i nā lole pale kūpono a me nā mīkina lima. S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. S22 – Mai hanu i ka lepo. S45 – Inā loaʻa ka pōʻino a i ʻole ka maikaʻi ʻole, e ʻimi koke i ka ʻōlelo aʻo kino (e hōʻike i ka lepili inā hiki.) S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. |
| UN ID | UN 2811 6.1/PG 3 |
| WGK Kelemānia | 3 |
| RTECS | YR0350000 |
| NUI FLUKA BRAND F | 10-23 |
| TSCA | T |
| HS Code | 29335995 |
| Nānā Hazard | Hoʻonanea/ʻawaʻawa loa |
| Papa Hazard | 6.1 |
| Hui Pūʻulu | III |
| Kaʻawaʻawa | LD50 waha i loko o ka Lapi: 230 mg/kg |
Hoʻolauna
Hoʻololi mua ʻia kēia huahana i nā nucleotides 5-fluoro-2-deoxyuracil i loko o ke kino, kahi e kāohi ai i ka thymine nucleotide synthase a pale i ka hoʻololi ʻana o nā nucleotides deoxyuracil i nā nucleotides deoxythymine, a laila e pale ai i ka biosynthesis DNA. Eia kekahi, ma ka pale ʻana i ka hoʻohui ʻana o ka uracil a me ka rotic acid i loko o ka RNA, loaʻa ka hopena o ka inhibiting RNA synthesis. ʻO kēia huahana kahi lāʻau lapaʻau kikoʻī o ka pōʻai cell, ka mea nui e kāohi ana i nā cell phase S.
E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou
