6-bromopyridine-2-carboxylic acid ethyl ester (CAS # 21190-88-5)
| Nā hōʻailona pōʻino | Xi – Hoʻohaunaele |
| Nā Code Risk | 36 - Hoʻonāukiuki i nā maka |
| Ka wehewehe palekana | 26 - Inā pili me nā maka, holoi koke me ka wai nui a ʻimi i ka ʻōlelo aʻoaʻo olakino. |
Hoʻolauna
ʻO ka waikawa ethyl ester he mea hoʻohuihui me ke ʻano kemika C8H8BrNO2. He wai waihoʻoluʻu me kahi ʻala kūikawā. Hiki ke hoʻoheheʻe ʻia ka hui i nā mea hoʻoheheʻe organik e like me ka ethanol, dimethylformamide a me benzene, a hiki ʻole ke hoʻoheheʻe ʻia i ka wai.
ʻO ka acid ethyl ester ka nui o nā noi i ka synthesis organik. Hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau no ka synthesis o kahi ākea o nā lāʻau lapaʻau a me nā moleke bioactive. Eia kekahi, hiki ke hoʻohana ʻia i ka pane Gormperman a me ka palladium-catalyzed cross-coupling reactions i ka synthesis organik.
ʻElua mau ala maʻamau no ka acid ethyl ester:
1. Loaʻa ia ma ka hopena o 6-bromopyridine a me chloroacetate, a laila hydrolyzed me ka alkali ma hope o ka hopena.
2. Ma ka 6-bromopyridine a me ka chloroacetic acid ester reaction, acid chloride, a laila e hana me ka waiʻona e loaʻa ai ka huahana.
Pono nā hana palekana i ka wā e hoʻohana ai a mālama ai i ka acid ethyl ester. He wai ʻaʻa ia a pono e mālama ʻia ma kahi ʻoluʻolu a maikaʻi ka ea, kahi mamao mai ke ahi a me nā wela kiʻekiʻe. Pono e ʻaʻahu ʻia nā mea pale kūpono, e like me nā mīkina lima lab a me nā maka aniani i ka wā o ka hana. Inā ʻai ʻia a pili paha me ka ʻili a i ʻole nā maka, holoi koke me ka wai nui a ʻimi i ke kōkua olakino.
