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huahana

9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one(CAS# 280761-97-9)

Waiwai Kemika:

ʻĀpana Molekala C12H19NO4
Molar Mass 241.28
ʻO ka mānoanoa 1.168±0.06 g/cm3(Wanamua)
Lae Boling 356.2±42.0 °C(Wanamua)
pKa -1.86±0.20(Wanamua)
Kūlana Waihona Hoʻopaʻa ʻia i loko o kahi maloʻo, lumi wela

Huahana Huahana

Huahana Huahana

 

Hoʻolauna

ʻO 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one(9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one) he hui lāʻau me ka mau waiwai penei:

 

1. Nānā: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one he pauka paʻa, maʻamau keʻokeʻo a keʻokeʻo paha.

 

2. Ka helu heheʻe: ʻO kona pae hoʻoheheʻe ma waena o 90-95 ° C.

 

3. Huina mole: C14H23NO3

 

4. Kaumaha Molekala: 257.34g/mol

 

ʻO nā hoʻohana nui o ka hui pū ʻia penei:

 

1. Ma ke 'ano he mea waena ma Organic Synthesis: 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one ka mea maʻamau i hoʻohana ʻia ma ke ʻano he waena i ka synthesis organik, ʻoi loa no ka synthesis o nā ketones.

 

2. Ka noiʻi kemika: Loaʻa i ka pūhui ka nui o nā noi ma nā kahua o ka synthesis organik a me ka chemistry pharmaceutical, e like me ka synthesis o nā lāʻau lapaʻau a i ʻole nā ​​​​mea mua.

 

ʻO ka hoʻomākaukau ʻana o 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one e pili ana i kēia mau ʻanuʻu:

 

1. ʻO ka mua, e hoʻomaka ana mai ka 9-chloro-7-oxa-9-azabicyclo [3.3.1] Nonane, ka hopena me BOC(tert-butoxycarbonyl), hoʻokomo ʻia ka hui BOC i loko o ka mole.

 

2. A laila, hoʻololi ʻia ka ʻātoma chlorine i pūʻulu ketone ma o ka hopena redox e hoʻohua i ka huahana 9-Boc-7-oxa-9-azabicyclo[3.3.1]nonan-3-one.

 

I ka hoʻohana ʻana i kēia pūhui, pono ʻoe e hoʻolohe i ka ʻike palekana aʻe:

 

1.9-boc-7-oxa-9-azabicyclo [3.3.1]nonan-3-one hiki ke hoʻonāukiuki i ka ʻili, nā maka, a me ka ʻōpū hanu, no laila pono e komo i nā mea pale kūpono e like me nā mīkina lima, nā pale maka, a me nā maka aniani i ka wā e hana ai.

 

2. E hōʻalo i ka hanu ʻana i ka lepo a i ʻole ke kinoea o ka mea hoʻohui a hōʻoia i ka hana ʻia ma kahi wahi hoʻoluʻu maikaʻi.

 

3. Pono e mālama ʻia ka hui mai ke ahi a me nā mea hoʻoheheʻe ʻia, a mālama ʻia i kahi maloʻo a maloʻo.

 

4. I ka hoʻohana ʻana a me ka hoʻohana ʻana i ka pūhui, e mālama pono i nā kaʻina hana palekana kūpono, e hahai i nā alakaʻi palekana a me nā hana hoʻokele.


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