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huahana

alpha-Arbutin(CAS# 84380-01-8)

Waiwai Kemika:

ʻĀpana Molekala C12H16O7
Molar Mass 272.25
ʻO ka mānoanoa 1.556±0.06 g/cm3 (Wānana ʻia)
Lae hehee 195-196°C
Lae Boling 561.6±50.0 °C(Wanamua)
Lae Flash 293.4°C
Ka hoʻoheheʻe Hiki ke hoʻoheheʻe ʻia i ka methanol, ethanol, DMSO a me nā mea hoʻoheheʻe ʻē aʻe
Puʻupuʻu mahu 1.9E-13mmHg ma 25°C
Ka nana aku ʻO ka pauka kristal keʻokeʻo
kala kala Keʻokeʻo i ke Keʻokeʻo
BRN 89675
pKa 10.10±0.15(Wanamua)
Kūlana Waihona 2-8°C
Hōʻike Hōʻike 1.65
MDL MFCD09838262
Na Waiwai Kino a Kimia Ka helu hehee 195-196°C

Huahana Huahana

Huahana Huahana

Pilikia a palekana

WGK Kelemānia 3

 

ʻIkepili

Nānā nui arbutin mea he hydroquinone glycoside pūhui, kemika inoa no 4-hydroxyphenyl-d-glucopyranoside (y), i loko o ka hua bear, bilberry a me nā mea kanu ʻē aʻe, he mea hou non-irritating, non-allergic, maoli whitening mea ikaika me ka ikaika like. Loaʻa iā Arbutin ʻelua mau pūʻulu hana a me ka hana i loko o kāna ʻano mole: hoʻokahi he koena glucose; ʻO kekahi pūʻulu hydroxyl phenolic. ʻIke ʻia ke ʻano kino o ka α-arbutin ma ke ʻano he keʻokeʻo i ka pauka hina hina, ʻoi aku ka maʻalahi i ka wai a me ka ethanol.
ka pono ʻOi aku ka maikaʻi o ka α-arbutin i nā ʻōpala i hana ʻia e UV Burns, ʻoi aku ka maikaʻi o ka anti-inflammatory, hoʻoponopono a me ka hopena keʻokeʻo. Hiki ke pale i ka hana a me ka waiho ʻana o ka melanin, wehe i nā kiko a me nā freckles.
ʻano hana ʻO ka hana keʻokeʻo o ka α-arbutin e hoʻopaʻa pololei i ka hana tyrosinase, ma laila e hōʻemi ai i ka hana ʻana o ka melanin, ma mua o ka hoʻohaʻahaʻa ʻana i ka hana melanin ma ke kāohi ʻana i ka ulu ʻana o ka cell a i ʻole tyrosinase gene expression. ʻOiai ʻo ka α-Arbutin he mea ʻoi aku ka maikaʻi a me ka palekana o ka mea keʻokeʻo keʻokeʻo, nui nā hui hoʻonaninani ma ka home a me nā ʻāina ʻē aʻe i hoʻohana i ka α-arbutin ma kahi o β-arbutin i mea hoʻohui keʻokeʻo.
Palapala noi ʻO ka alpha-Arbutin kahi kemika e like me ka arbutin, hiki ke kāohi i ka hana a me ka waiho ʻana o ka melanin, wehe i nā kiko a me nā freckles. Hōʻike nā hopena i hiki i ka arbutin ke kāohi i ka hana o tyrosinase ma kahi haʻahaʻa haʻahaʻa, a ʻoi aku ka maikaʻi o kona hopena pale i ka tyrosinase ma mua o ka arbutin. Hiki ke hoʻohana ʻia ka alpha-arbutin ma ke ʻano he mea keʻokeʻo i nā mea hoʻonaninani.
ka hoʻomaʻemaʻe a me ka ʻike ʻO ka hāpana i loaʻa ma ka hopena ua unuhi muaʻia me ka ethyl acetate, a laila unuhiʻia me ka n-butanol, ua hōʻiliʻiliʻia nā mea hoʻohālike e ka evaporation ma luna o ka rotary evaporator a centrifuged. Ua kālailai ʻia ka supernatant e HPLC a ua hoʻohālikelike ʻia me ka HPLC chromatogram o α-arbutin, inā paha he like ka manawa paʻa o ka hāpana a me ka α-arbutin, a inā paha i loko o ka hāpana he α-Arbutin ka mea i ʻike mua ʻia.

Ua ʻike ʻia ka huahana ma hope o ka unuhi ʻana a me ka hoʻomaʻemaʻe ʻana e ke ʻano ion maikaʻi o LC-ESI-MS/MS. Ma ka hoʻohālikelike ʻana i ka nui molekala pili o ka hua α-bear me ka nui molepili pili o ka maʻamau α-arbutin, hiki ke hoʻoholo inā he α-arbutin ka huahana.

Hoʻohana Hiki i ka α-arbutin ke kāohi i ka hana tyrosinase ma kahi haʻahaʻa haʻahaʻa, ʻoi aku ka maikaʻi o kona hopena pale i ka tyrosinase ma mua o ka arbutin.

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