N-(tert-Butoxycarbonyl)-L-aspartic acid (CAS # 13726-67-5)
Pilikia a palekana
| Nā hōʻailona pōʻino | Xn – Poino |
| Nā Code Risk | R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. |
| Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S36 – E komo i nā lole pale kūpono. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 3 |
| HS Code | 2924 19 00 |
N-(tert-Butoxycarbonyl)-L-aspartic acid (CAS# 13726-67-5) Hoʻomaka
ʻO ka waikawa Boc-L-aspartic kahi pūhui organik i hoʻohana mau ʻia ma ke ʻano he hui pale i ka peptide synthesis. ʻO C13H19NO6 kona paona kemika a ʻo kona kaumaha mole 293.29. Hōʻike ʻo Boc i ka N-tert-butoxycarbonyl.
ʻO Boc-L-aspartic acid ka nui o nā waiwai penei:
1. Nani: colorless crystalline pauka;
2. wahi hehee: e pili ana i 152-155 ℃;
3. Solubility: Hiki ke hoʻoheheʻe ʻia i loko o kekahi mau mea hoʻoheheʻe organik, e like me ka dimethyl sulfoxide a me dichloromethane, hiki ʻole ke hoʻoheheʻe ʻia i ka wai;
4. kūpaʻa: hiki ke decomposition i ka hihia o ka oxidant ikaika a me ka māmā.
ʻO ka hoʻohana nui o ka waikawa Boc-L-aspartic ma ke ʻano he hui pale i ka peptide synthesis. Mālama ia i ka hui amine ma ke kaulahao ʻaoʻao o L-aspartic acid e pale i nā hopena makemake ʻole. I ka wā o ka peptide synthesis, hui pū ʻo Boc-L-aspartic acid me nā amino acids a i ʻole nā ʻāpana peptide e hana i nā kaulahao peptide hou. Ma hope o ka pau ʻana o ka synthesis, hiki ke hoʻoneʻe ʻia ka hui pale e ka mālama ʻana i ka waikawa e loaʻa ai ka peptide a i ʻole ka protein.
Hoʻomākaukau ʻia ka waikawa Boc-L-aspartic e nā ʻano hana synthetic i ʻike ʻia. ʻO ka pōkole, hiki ke hoʻohui ʻia ka L-aspartic acid ma ka hana ʻana i ka waikawa L-aspartic me ka t-Boc-L acid a me ka dimethylformamide. Hiki ke loaʻa nā ʻano hana synthetic i loko o ka palapala kemika pili.
E pili ana i ka ʻike palekana, pono ʻoe e makaʻala i nā ʻōlelo aʻe:
1. ʻO ka waika Boc-L-aspartic he mea kemika me kekahi mea ʻona. Pono e mālama ʻia nā hana pale kūpono i ka wā o ka hana, e like me ke komo ʻana i nā mīkina lima, nā maka aniani a me nā lole ʻenehana;
2. pale i ka inhalation o ka pauda a i ʻole ka hopena, e pale i ka pili ʻana me ka ʻili a me nā maka;
3. I ka hoʻohana ʻana a me ka lawelawe ʻana i ka waikawa Boc-L-aspartic, pono e hoʻopaʻa ʻia a mālama ʻia e pale aku i ka hoʻopili ʻana me nā oxidants a me ka mālamalama ikaika;
4. I ka wā e pili ana i ka ʻōpala waika Boc-L-aspartic, pono e hoʻolei ʻia e like me nā kānāwai kūloko.
ʻO Boc-L-aspartic acid ka nui o nā waiwai penei:
1. Nani: colorless crystalline pauka;
2. wahi hehee: e pili ana i 152-155 ℃;
3. Solubility: Hiki ke hoʻoheheʻe ʻia i loko o kekahi mau mea hoʻoheheʻe organik, e like me ka dimethyl sulfoxide a me dichloromethane, hiki ʻole ke hoʻoheheʻe ʻia i ka wai;
4. kūpaʻa: hiki ke decomposition i ka hihia o ka oxidant ikaika a me ka māmā.
ʻO ka hoʻohana nui o ka waikawa Boc-L-aspartic ma ke ʻano he hui pale i ka peptide synthesis. Mālama ia i ka hui amine ma ke kaulahao ʻaoʻao o L-aspartic acid e pale i nā hopena makemake ʻole. I ka wā o ka peptide synthesis, hui pū ʻo Boc-L-aspartic acid me nā amino acids a i ʻole nā ʻāpana peptide e hana i nā kaulahao peptide hou. Ma hope o ka pau ʻana o ka synthesis, hiki ke hoʻoneʻe ʻia ka hui pale e ka mālama ʻana i ka waikawa e loaʻa ai ka peptide a i ʻole ka protein.
Hoʻomākaukau ʻia ka waikawa Boc-L-aspartic e nā ʻano hana synthetic i ʻike ʻia. ʻO ka pōkole, hiki ke hoʻohui ʻia ka L-aspartic acid ma ka hana ʻana i ka waikawa L-aspartic me ka t-Boc-L acid a me ka dimethylformamide. Hiki ke loaʻa nā ʻano hana synthetic i loko o ka palapala kemika pili.
E pili ana i ka ʻike palekana, pono ʻoe e makaʻala i nā ʻōlelo aʻe:
1. ʻO ka waika Boc-L-aspartic he mea kemika me kekahi mea ʻona. Pono e mālama ʻia nā hana pale kūpono i ka wā o ka hana, e like me ke komo ʻana i nā mīkina lima, nā maka aniani a me nā lole ʻenehana;
2. pale i ka inhalation o ka pauda a i ʻole ka hopena, e pale i ka pili ʻana me ka ʻili a me nā maka;
3. I ka hoʻohana ʻana a me ka lawelawe ʻana i ka waikawa Boc-L-aspartic, pono e hoʻopaʻa ʻia a mālama ʻia e pale aku i ka hoʻopili ʻana me nā oxidants a me ka mālamalama ikaika;
4. I ka wā e pili ana i ka ʻōpala waika Boc-L-aspartic, pono e hoʻolei ʻia e like me nā kānāwai kūloko.
E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou
