Boc-D-Glutamic acid 5-benzyl ester（CAS# 35793-73-8)
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 3 |
Hoʻolauna
ʻO Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH) he mea hoʻohuihui. ʻO kēia ka wehewehe ʻana o kona ʻano, hoʻohana, hana a me ka ʻike palekana:
ʻAno:
-Nani: ʻO ka pauka crystalline keʻokeʻo
-Poloke mole: C20H25NO6
-Molecular Kaumaha: 379.41
-kahi hoʻoheheʻe: 118-120 ℃
-Solubility: Hiki ke hoʻoheheʻe ʻia i kekahi mau mea hoʻoheheʻe organik, e like me ka methanol a me ka dichloromethane
E hoʻohana:
- Hoʻohana maʻamau ʻia ʻo Boc-D-Glu(OBzl)-OH i ke kahua o ka synthesis lāʻau a me ka synthesis peptide.
-Hiki ke hoʻohana ʻia ma ke ʻano he pūʻulu pale no nā peptides e pale i ka pūʻulu hana hydroxyl o ka glutamic acid i ka wā o ka synthesis e pale ai i nā hopena i makemake ʻole ʻia i ka wā o ka hopena.
Kaʻina hoʻomākaukau:
- Hoʻomākaukau maʻamau ʻia ʻo Boc-D-Glu(OBzl)-OH e ka synthesis kemika.
-ʻO ka mua, hoʻokomo ʻia ka tert-butoxycarbonyl (Boc) i loko o ka molekele glutamic acid e hana i ka tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-A laila, hoʻokomo ʻia kahi hui benzyl (Bzl) i loko o ka pūʻulu hydroxyl o ka waikawa glutamic e hana i ka Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH).
ʻIke palekana:
- ʻO ka Boc-D-Glu(OBzl)-OH he mea hoʻohuihui mea ola, hiki ke hoʻonāukiuki i ke kino o ke kanaka.
-I ka wā e hoʻohana ai, e makaʻala e pale i ka pili ʻana me ka ʻili, nā maka a me ka ʻōpū hanu.
-Ma nā hana hoʻokolohua a i ʻole ka hana ʻenehana, pono e hoʻohana ʻia nā lako pale pilikino kūpono, e like me nā mīkina lima, nā aniani pale a me nā maka pale.
- E mālama i ka pahu mai ke ahi a me nā mea hoʻoheheʻe, e hoʻopaʻa i ka pahu, a waiho i kahi maloʻo a maloʻo.
E ʻoluʻolu e hoʻomaopopo he ʻike maʻamau wale nō kēia a ʻaʻole pili i nā kūlana hoʻokolohua kikoʻī a me nā hana palekana. Ma mua o ka hoʻohana ʻana i kēia pūhui, ʻōlelo ʻia e nīnau i ka pepa ʻikepili palekana palekana (MSDS) a hahai i nā hana palekana kūpono.
