Boc-L-aspartic acid 1-benzyl ester（CAS# 30925-18-9)

Hoʻolauna

ʻO Boc-Asp-OBzl(Boc-Asp-OBzl) kahi hui i loaʻa nā waiwai penei:

1. Nānā: Paʻa keʻokeʻo keʻokeʻo.

2. Huina mole: C24H27N3O7.

3. Kaumaha Molekala: 469.49g/mol.

4. Ka helu hehee: ma kahi o 130-134 ° C.

Hoʻohana nui ʻia ʻo Boc-Asp-OBzl i ka biochemistry a me ka synthetic organic chemistry, i hoʻohana pinepine ʻia i ka synthesis o peptides, proteins a me nā lāʻau lapaʻau, me nā hoʻohana aʻe:

1. Peptide synthesis: Ma ke ʻano o ka hui pale (Boc protecting group), hiki ke pale ʻia ka hui amino i loko o ka aspartic acid amino acid.

2. Ka noiʻi lāʻau: no ka hoʻohui ʻana i nā lāʻau peptide me ka anti-inflammatory, anti-tumor a me ka hana hoʻoponopono immune.

3. Pane Enzyme: Hiki ke hoʻohana ʻia ʻo Boc-Asp-OBzl no ka enzyme catalyzed reaction substrate.

ʻO ke ʻano o ka hoʻomākaukau ʻana i ka Boc-Asp-OBzl penei:

ʻO ka waikawa Aspartic a me ka benzoyl chloride e hoʻoheheʻe ʻia e hana i ka tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), i hoʻopili ʻia me ka sodium hexoxide e loaʻa ai kahi mea waena ma ke ʻano o N-hexanoate. ʻO ka mea hope loa, loaʻa iā ia kahi hopena benzoylation e hana ai i ka Boc-Asp-OBzl.

E noʻonoʻo i ka ʻike palekana i ka wā e hoʻohana ai i ka Boc-Asp-OBzl:

1. Hiki i ka hui ke hoʻoulu i ka huhū a me nā hopena maʻi i ke kino o ke kanaka, a pono e pale ʻia ka pili pono ʻana me ka ʻili a me nā maka.

2. Pono e mālama ʻia nā hana palekana pilikino i ka wā e hana ai, e like me ke komo ʻana i nā mīkina lima a me nā maka.

3. E mālama i kahi maloʻo a hoʻopaʻa ʻia i ka wā o ka mālama ʻana, a mālama i ke ahi a me ka oxidant.

4. I ka hoʻohana ʻana a me ka lawelawe ʻana iā Boc-Asp-OBzl, e ʻoluʻolu e hahai i nā kaʻina hana hoʻokolohua kūpono a me ka hana palekana.

E ʻoluʻolu e hoʻomaopopo i ka wā e hoʻohana ai iā Boc-Asp-OBzl a i ʻole nā ​​​​mea kemika, pono ʻoe e hahai pono i nā alakaʻi hana palekana e pili ana, a mālama i ka pale pilikino a me ka loiloi pilikia e like me ke kūlana maoli.