BOC-L-Phenylglycine（CAS# 2900-27-8)

Hoʻolauna

ʻO ka N-Boc-L-Phenylglycine kahi mea hoʻohui i hoʻokumu ʻia e ka hoʻokumu ʻana i kahi paʻa kemika ma waena o ka hui amino (NH2) o glycine a me ka hui carboxyl (COOH) o ka waikawa benzoic. Aia i loko o kona hale kahi hui pale (Boc group), ʻo ia ka pūʻulu tert-butoxycarbonyl, i hoʻohana ʻia no ka pale ʻana i ka reactivity o ka hui amino.

Loaʻa iā N-Boc-L-phenylglycine nā waiwai penei:

- Ke ʻano: Paʻa keʻokeʻo keʻokeʻo

- Solubility: Hiki ke hoʻoheheʻe ʻia i kekahi mau mea hoʻoheheʻe organik, e like me dimethylformamide (DMF), dichloromethane, etc.

Hoʻohana maʻamau ʻia ʻo N-Boc-L-phenylglycine i nā hopena he nui i ka synthesis organik, ʻoi loa no ka synthesis o nā pūhui peptide. Hiki ke hoʻopau ʻia ka pūʻulu pale Boc e nā kūlana acidic, i hiki ai i ka pūʻulu amino ke reactive a laila hoʻokō i nā hopena ma hope. Hiki ke hoʻohana ʻia ʻo N-Boc-L-phenylglycine ma ke ʻano he derivative no ke kūkulu ʻana i nā kikowaena chiral i ka peptide synthesis.

ʻO ka hoʻomākaukau ʻana o N-Boc-L-phenylglycine e hana nui ʻia e nā pae aʻe:

Hoʻopili ʻia ʻo Glycine me ka waikawa benzoic e loaʻa ai ka ester benzoic acid-glycinate.

Me ka hoʻohana ʻana i ka hopena lithium borotrimethyl ether (LiTMP), ua protonated ka benzoic acid-glycinate ester a hana ʻia me Boc-Cl (tert-butoxycarbonyl chloride) e loaʻa ai ka N-Boc-L-phenylglycine.

- He mea hoʻonāukiuki paha ka N-Boc-L-phenylglycine i ka maka, ka ʻili, a me ka ʻōpū hanu a pono e pale ʻia i ka wā e hoʻohana ai.

- Pono e hoʻohana ʻia nā mea pale pilikino e like me nā mīkina lima laboratory, nā aniani palekana, a me nā mea ʻē aʻe i ka wā o ka hana.

- Pono e hana ʻia i loko o kahi keʻena hoʻokolohua maikaʻi.

- Hōʻalo i ka hoʻopili ʻana me nā oxidants a me nā waikawa ikaika i ka wā e mālama ai.

- Inā ale ʻia a inhaled paha, e ʻimi koke i ka lāʻau lapaʻau, e lawe mai i kahi pahu o ka hui, a hāʻawi i ka ʻike palekana e pono ai i ke kauka.