Carbobenzyloxy-beta-alanine（CAS# 2304-94-1)
| Nā hōʻailona pōʻino | Xn – Poino |
| Nā Code Risk | R22 – Poino ke aleia R41 – Ka pilikia o ka poino nui i na maka |
| Ka wehewehe palekana | S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S39 - Hoʻohana i ka pale maka / maka. |
| WGK Kelemānia | 2 |
| HS Code | 29242990 |
| Papa Hazard | HOOLAHA |
Hoʻolauna
He hui kino ia i pani ʻia ai ka pūʻulu carboxyl (-COOH) i loko o ka mole alanine i loko o ka hale e kahi hui benzyloxycarbonyl (-Cbz).
Nā waiwai o ka hui:
-Nani: ʻO ka pauka aniani keʻokeʻo
-Ke kumu molekole: C12H13NO4
-Molecular kaumaha: 235.24g/mol
-Lae hehee: 156-160 ° C
ʻO nā mea hoʻohana nui e like me kēia:
-Ma ke kahua o ka synthesis organik, hiki ke hoʻohana ʻia ma ke ʻano he waena no ka synthesis o nā mea hoʻohui organik paʻakikī.
-Ma ke ʻano he hui pale no nā lāʻau polypeptide synthetic, hoʻohana ʻia ia e pale i nā koena alanine.
-No ka noiʻi ʻana a me ka hoʻomākaukau ʻana i nā molekole organik ʻē aʻe.
Hiki ke hoʻokaʻawale ʻia ke ʻano hoʻomākaukau i nā ʻanuʻu penei:
1. ʻO ka hopena o ka benzyl chlorocarbamate me ka sodium carbonate e loaʻa ai ka benzyl N-CBZ-methylcarbamate (N-benzyloxycarbonylmethylaminoformate).
2. E hana i ka huahana i loaʻa ma ka ʻanuʻu mua me ka solution sodium hydroxide e loaʻa ai ka N-CBZ-β-alanine.
E pili ana i ka ʻike palekana:
-ʻO ka mea maʻamau i manaʻo ʻia he palekana, akā pono mau nā hana hana kūpono.
-E pale i ka pili ʻana me ka ʻili, nā maka a me ka waha i ka wā e hoʻohana ai.
-E hoʻohana i nā mīkina lima pale kūpono, nā maka aniani, a me nā ʻaʻahu lab ke hana i nā hoʻokolohua.
-E hōʻalo i ka hanu ʻana i ka lepo mai ka hui.
- Pono e mālama ʻia ka pūhui ma kahi maloʻo, maloʻo, a hoʻokaʻawale ʻia mai nā mea hiki ke ahi, nā mea ʻona a me nā mea ʻē aʻe.
Pono e hoʻomaopopo ʻia ʻo ka ʻike i hāʻawi ʻia ma ʻaneʻi no ka ʻike wale nō, a ʻo ka manual hoʻokolohua kūpono a me ka pepa ʻikepili palekana kemika pono e kūkākūkā ʻia ma mua o ka hoʻohana ʻana i ka pūhui, a e like me nā lula palekana no ka hana.
