CBZ-D-ALLO-ILE-OH（CAS# 55723-45-0)

Hoʻolauna

ZD-allo-Ile-OH . ʻO DCHA (ZD-allo-Ile-OH · DCHA) he mea hoʻohuihui mea ola a me ka reagent no ka pale ʻana i nā waikawa amino. ʻO kēia ka wehewehe ʻana o kona ʻano, hoʻohana, hana a me ka ʻike palekana:

ʻAno:

-Ke kimeka: C23H31NO5

-Molecular kaumaha: 405.50g/mol

-Ke ʻano: Paʻa keʻokeʻo keʻokeʻo

-Ka helu heheʻe: 105-108°C

-Solubility: Hiki ke hoʻoheheʻe ʻia e like me ka acetone, ether, dichloromethane, insoluble i ka wai.

E hoʻohana:

- ZD-allo-Ile-OH . ʻO DCHA kahi reagent i hoʻohana ʻia e pale i nā waikawa amino. Ma ka hoʻokomo ʻana i kahi pūʻulu Cbz ma ka pūʻulu amino o kahi waikawa amino, hiki ke pale ʻia ka hoʻololi ulia ʻana o ka pūʻulu amino i loko o kahi hopena synthesis kemika.

-Hoʻohana pinepine ʻia i ka peptide synthesis, ʻoi loa no ka synthesis o nā kaʻina peptide me nā hana kūikawā a i ʻole nā ​​​​hana.

Kaʻina hoʻomākaukau:

- ZD-allo-Ile-OH. Hoʻomaka maʻamau ka hoʻomākaukau ʻana o DCHA mai D-isoleucine, a laila hana pū me Cbz anhydride no ka esterification e hoʻolauna i ka hui pale Cbz. ʻO ka hope loa, ua hoʻopili ʻia ka DCHA (dichloroformic acid) me ka amino acid e hana i ka paʻakai pili.

ʻIke palekana:

- ZD-allo-Ile-OH . ʻAʻole ʻawaʻawa ka DCHA, akā pono e mālama ʻia me ka akahele. E hōʻalo i ka pili ʻana me ka ʻili a me nā maka, e hoʻohana i nā mīkina lima pale a me nā aniani inā pono.

-I ka wā e hoʻohana ai, pono e hahai ʻia nā kaʻina hana hana maʻamau a pono e hoʻohana ʻia nā mea hoʻoheheʻe kūpono.

-I ka mālama ʻana, e mālama i ka pūhui ma kahi maloʻo a maʻalili ma kahi mamao mai nā kumu o ke ahi a me nā lapalapa ākea.