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huahana

Cbz-L-3-Cyclohexyl Alanine(CAS# 25341-42-8)

Waiwai Kemika:

ʻĀpana Molekala C17H23NO4
Molar Mass 305.37
ʻO ka mānoanoa 1.167
Lae Boling 501.4±43.0 °C(Wānana ʻia)
pKa 4.00±0.10(Wanamua)
Kūlana Waihona 2-8°C

Huahana Huahana

Huahana Huahana

WGK Kelemānia 3

 

Hoʻolauna

ʻO Z-3-CYCLOHEXYL-L-ALANINE (Z-3-CYCLOHEXYL-L-ALANINE) he mea hoʻohui kino me nā waiwai penei:

 

1. Nani: kalakala kala ole a pauda paa.

 

2. Solubility: i loko o kekahi mau mea hoʻoheheʻe organik (e like me dimethyl sulfoxide, methanol) hiki ke hoʻoheheʻe, hikiʻole ke hoʻoheheʻe i ka wai.

 

3. Ka helu hehee: ma kahi o 128-134 ℃.

 

4. ʻO ka hana kemika: aia i loko o kona hale ka hui cyclohexane cyclic a me kahi kaulahao ʻaoʻao α-amino acid.

 

Loaʻa iā Z-3-CYCLOHEXYL-L-ALANINE kekahi mau noi a me nā mea hoʻohana, me:

 

1. Ka noiʻi biochemical: ma ke ʻano he kikowaena no ka hoʻohui ʻana i nā peptides, nā protein a i ʻole nā ​​lāʻau lapaʻau.

 

2. Hoʻomohala lāʻau: hiki ke hoʻohana ʻia e like me ka mea noiʻi o nā lāʻau anti-tumor, no ka ʻōnaehana lawe lāʻau.

 

3. Organic Synthesis: ma ke ʻano he mea hoʻomaka koʻikoʻi no ka hoʻohui ʻana o nā pūhui organik me nā hale kikoʻī.

 

ʻO ke ʻano o ka hoʻomākaukau ʻana i ka Z-3-CYCLOHEXYL-L-ALANINE penei:

 

Ma lalo o ka palekana naikokene, ua hoʻoheheʻe ʻia ʻo L-cyclohexylalanine i ka dimethyl sulfoxide, ua hoʻohui ʻia ka sodium p-trimethylmethane e hoʻoheheʻe ʻia, a ua hoʻohui ʻia ka dibutylene carbonate a me ka dihydroxy benzoin ketone (CbzCl). Hoʻoulu ʻia ka hui ʻana i ka lumi wela no kekahi manawa, a laila hoʻoheheʻe ʻia me ka wai, hoʻokaʻawale ʻia ka waikawa, crystallized, holoi ʻia a maloʻo e hāʻawi i ka huahana.

 

No ka ʻike palekana, ʻaʻole i hōʻike ʻia nā noiʻi toxicological kikoʻī Z-3-CYCLOHEXYL-L-ALANINE. Pono e hoʻohana ʻia nā hana hoʻokolohua kūpono, e like me ke komo ʻana i nā mīkina lima lima a me nā makaaniani hale hana, a me ka hana ʻana i nā kūlana ea maikaʻi ke hoʻohana ʻia i ka wā e lawelawe ai a hoʻohana i ka mea. Inā loaʻa ka ʻili a i ʻole nā ​​maka, holoi koke me ka wai nui a ʻimi koke i ke kōkua olakino.


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