D-1-N-Boc-prolinamide（CAS# 35150-07-3)
| Nā hōʻailona pōʻino | Xn – Poino |
| Nā Code Risk | 22 - Poino ke aleia |
| Ka wehewehe palekana | 24/25 - E pale i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 2 |
Hoʻolauna
ʻO D-1-N-Boc-prolinamide(D-1-N-Boc-prolinamide) he mea hoʻohuihui me nā waiwai aʻe:
1. Nānā: Paʻa keʻokeʻo keʻokeʻo.
2. kumu mole: C14H24N2O3.
3. Molecular kaumaha: 268.35g / mol.
4. helu hehee: e pili ana i 75-77 degere Celsius.
5. Solubility: Hiki ke hoʻoheheʻe ʻia i ka wai a me kekahi mau mea hoʻoheheʻe kūlohelohe, e like me ka chloroform, ethanol a me dimethyl sulfoxide.
ʻO kekahi o ka hoʻohana nui ʻana o D-1-N-Boc-prolinamide ma ke ʻano he chiral reagent no ka synthesis asymmetric i ka synthesis kemika organik. Hiki ke hoʻohana ʻia ma ke ʻano he papa kūkulu hale o kahi iwi chiral e hoʻolauna i ka ʻike chiral ma o kāna kikowaena chiral, a laila e loaʻa ai nā pūhui chiral. Eia kekahi, hiki ke hoʻohana ʻia ma ke ʻano he waena no ka synthesis o nā lāʻau lapaʻau, pesticides a me nā moleke bioactive.
ʻO ke ʻano o ka hoʻomākaukau ʻana i ka D-1-N-Boc-prolinamide ka mea maʻamau e hana i ka N-Boc-L-proline me ka tert-butyl chloroformate ma lalo o nā kūlana alkaline e hoʻohua ai i ka N-Boc-L-proline methyl ester, a laila mālama ʻia i ka wela hoʻopuka i ka huahana i manaʻo ʻia.
E pili ana i ka ʻike palekana, ʻaʻohe D-1-N-Boc-prolinamide haʻawina kikoʻī. Eia nō naʻe, ma ke ʻano laulā, pono e hahai ʻia nā hana palekana maʻamau, a pono e mālama ʻia nā mea pale e like me nā mīkina lima, nā maka aniani a me nā lole pale i ka wā e hoʻohana ai. Eia kekahi, pono e mālama ʻia i loko o kahi pahu pani e pale aku ai i ka hoʻopili ʻana me ka oxygen a me ka wai. Inā hoʻohālua ʻia a pili ʻole paha me ka ʻili a me nā maka, holoi koke me ka wai nui a ʻimi i ke kōkua olakino. Inā hoʻolei ʻia ka ʻōpala, pono e mālama ʻia nā lula kūloko. ʻOi aku ka maikaʻi o ka hoʻohana ʻana a me ka mālama ʻana i ka pūhui ma lalo o ke alakaʻi ʻana a kekahi me ka ʻoihana ʻoihana i ka kemika.
