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D(-)-Glutamic acid(CAS# 6893-26-1)

Waiwai Kemika:

ʻĀpana Molekala C5H9NO4
Molar Mass 147.13
ʻO ka mānoanoa 1.5380
Lae hehee 200-202°C (subl.)(kumu)
Lae Boling 267.21°C (manaʻo koʻikoʻi)
Kahuli kiko'ī(α) -31.3 º (c=10, 2 N HCl)
Lae Flash 155.7°C
Hiki i ka wai 7 g/L (20 ºC)
Ka hoʻoheheʻe Wai (Lili iki)
Puʻupuʻu mahu 2.55E-05mmHg ma 25°C
Ka nana aku Keokeo aniani
kala kala Keʻokeʻo a keʻokeʻo
ʻO Merck 14,4469
BRN 1723800
pKa pK1:2.162(+1);pK2:4.272(0);pK3:9.358(-1) (25°C)
Kūlana Waihona E mālama ma kahi pouli, Hoʻopaʻa ʻia i kahi maloʻo, Ke ana wela o ka lumi
Hōʻike Hōʻike 1.4210 (manaʻo)
MDL MFCD00063112
Na Waiwai Kino a Kimia Keʻokeʻo Crystal a i ʻole ka pauka crystalline; Hiki ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka ethanol, ʻaʻole hiki ke hoʻoheheʻe ʻia i ka etera; ʻO ka hoʻololi ʻike kikoʻī [α]20D-30.5 °(0.5-2 mg/mL, 6mol/L HCl),LD50 (kanaka, intravenous) 117 mg/kg.
Hoʻohana Nā lāʻau lapaʻau amino acid.
Haʻawina in vitro ʻO nā ʻakika d-amino like ʻole, e like me D-serine, D-aspartic acid (D-Asp), a me D-glutamic acid (D-Glu) i ʻike nui ʻia i loko o nā mammals me nā kānaka a ke manaʻo ʻia nei lākou nā moho nā mea hoʻoikaika kino physiologically hou a / a i ʻole nā ​​biomarkers. Kāohi ʻo D-[Asp/Glu] (4 mg/mL) i ka hoʻopaʻa ʻana o IgE (75%) i nā pīkī aʻo D-Glu, D-Asp ʻaʻohe hopena pale. He kikoʻī ʻo IgE no D-[Asp/Glu] a hiki paha iā ia ke wehe i ka IgE a i ʻole ka hōʻemi ʻana i ka paʻa ʻana o IgE i nā allergens pīni.
In vivo haʻawina Ke nānā ʻia nei ka D-glutamic acid ma ke ʻano he modulator o ka neʻe neuronal a me ka huna ʻana o ka hormonal. Hoʻopili wale ʻia e D-aspartate oxidase i nā mammals. Ma hope o ka hoʻokele intraperitoneal, hoʻopili ʻia ʻo L-glutamate ma o ka a-ketoglutarate, aʻo D-glutamate i hoʻololi ʻia i n-pyrrolidone carboxylic acid. Hoʻololi ʻia ke kalapona 2 o D- a me L-glutamate i ka cecum i ka methyl carbon o ka acetate. Na ka ʻiole a me ka puʻupaʻa e hoʻohuli i ka D-glutamic acid i n-pyrrolidone carboxylic acid.

Huahana Huahana

Huahana Huahana

Nā hōʻailona pōʻino Xi – Hoʻohaunaele
Nā Code Risk 36/37/38 – Hoʻonanea i nā maka, ʻōnaehana hanu a me ka ʻili.
Ka wehewehe palekana S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka.
S36 – E komo i nā lole pale kūpono.
S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
WGK Kelemānia 3
NUI FLUKA BRAND F 10
TSCA ʻAe
HS Code 29224200

 

Hoʻolauna

ʻO D-glutenate, ka mea i kapa ʻia ʻo D-glutamic acid a i ʻole ka sodium D-glutamate, he waikawa amino kūlohelohe me nā ʻano waiwai nui a me nā hoʻohana.

 

ʻO nā waiwai nui o D-gluten penei:

Ka ʻono ʻoluʻolu: ʻO D-gluten kahi mea hoʻonui umami e hoʻonui ai i ka ʻono umami o nā meaʻai a hoʻonui i ka ʻono o nā meaʻai.

Pākuʻi meaʻai: ʻO D-gluten kekahi o nā waikawa amino pono no ke kino o ke kanaka a he hana koʻikoʻi i ka mālama ʻana i ke olakino kanaka.

Paʻa kemika: Paʻa paʻa ka D-gluine ma lalo o nā kūlana ʻakika a hiki nō ke mālama i ke kūpaʻa pili ma lalo o nā kūlana wela kiʻekiʻe.

 

Hoʻohana i ka D-Gluten Acid:

Ka noiʻi biochemical: Ua hoʻohana nui ʻia ka D-glutamic acid i ka noiʻi biochemical a me nā hoʻokolohua e aʻo ai i kona hopena biochemical a me nā ala metabolic i nā mea ola.

 

ʻO ke ʻano o ka hoʻomākaukau ʻana o D-gluten e loaʻa nui ʻia e ka microbial fermentation a i ʻole synthesis chemical. ʻO ka hana ʻana o ka microbial fermentation i kēia manawa ke ʻano hoʻomākaukau nui, me ka hoʻohana ʻana i kekahi mau kānana e hana i ka nui o ka D-glutamic acid ma o ka fermentation. Hoʻohana maʻamau ka synthesis i nā mea waiwai synthetic a me nā kūlana hoʻohālikelike kikoʻī e synthesize D-gluten acid.

 

ʻIke palekana o D-Gluten: Ma ka laulā, palekana ʻo D-Gluten ma lalo o nā kūlana o ka hoʻohana pono a me ka mālama ʻana. Eia kekahi, no kekahi mau heluna kanaka, e like me nā kamaliʻi a me nā wahine hāpai, a i ʻole ka poʻe me ka glutamate sensitivity, ʻoi aku ka maikaʻi o ka hoʻohana ʻana a i ʻole ka pale ʻana i ka D-glutamate me ka hoʻohaʻahaʻa.


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