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D-Glutamine（CAS# 5959-95-5) Ki‘i Mana‘o
  • D-Glutamine（CAS# 5959-95-5) 1

D-Glutamine（CAS# 5959-95-5)

Waiwai Kemika:

ʻĀpana Molekala C5 H10 N2 O3
Molar Mass 146.14
ʻO ka mānoanoa 1.3394 (manaʻo koʻikoʻi)
Lae hehee 184-185 °C
Lae Boling 265.74°C (manaʻo koʻikoʻi)
Kahuli kiko'ī(α) -32 º (589nm, c=10, N HCl)
Hiki i ka wai 42.53g/L (ʻaʻole i ʻōlelo ʻia ka mahana)
Ka hoʻoheheʻe Hiki ke hoʻoheheʻe ʻia i ka wai (9 mg/ml ma 25 °C), DMSO (<1 mg/ml ma 25 °C), a me ka ethanol (<1 mg/m.
Ka nana aku ʻO ka pauka kristal keʻokeʻo
kala kala Keʻokeʻo
BRN 1723796
pKa 2.27±0.10(Wanamua)
Kūlana Waihona E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Hōʻike Hōʻike -33 ° (C=5, 5mol/LH
MDL MFCD00065607
Na Waiwai Kino a Kimia Lae hehee: 185
Haʻawina in vitro ʻO Glutamine kahi waikawa amino koʻikoʻi i loko o ka ʻōnaehana nūnū waena (CNS), e pāʻani ana i kahi kuleana koʻikoʻi i ka pōʻai glutamate/GABA-Glutamine (GGC). I ka GGC, ua hoʻololi ʻia ʻo Glutamine mai nā astrocytes i nā neurons, kahi e hoʻopiha ai i nā loko neurotransmitter inhibitory a excitatory. Ua hoʻohana ʻia ʻo D-Glutamine e aʻo i kāna kuleana i ka hāʻawi ʻana i ka pale mai ka acetaldehyde-induced disruption o ka hana pale ma Caco-2 cell monolayer. ʻO ke kuleana o L-Glutamine i ka pale ʻana i ka epithelium intestinal mai ka acetaldehyde-induced disruption of barrier function i loiloi ʻia ma Caco-2 cell monolayer. Ua ho'ēmi ka L-Glutamine i ka emiʻana o ka acetaldehyde-induced i ke kū'ē uila transepithelilal a me ka hoʻonui i ka permeability i ka inulin a me ka lipopolysaccharide i ka manawa a me keʻano o ka hopena; ʻO D-Glutamine, L-aspargine, L-arginine, L-lysine, a i ʻole L-alanine ʻaʻole i hoʻopuka i kahi pale nui. ʻAʻole hiki i ka D-Glutamine ke hoʻoikaika i ka emi ʻana o ka acetaldehyde i ka TER a me ka hoʻonui ʻana i ka inulin flux. ʻO D-Glutamine a i ʻole glutaminase inhibitor ma o lākou iho ʻaʻole i hoʻololi i ka TER a i ʻole ka inulin flux i ka mana a i ʻole nā ​​​​mea hoʻohana i ka acetaldehyde-treated cell monolayers. ʻO ka nele o ka hopena o D-Glutamine i ka pale ʻana mai ka acetaldehyde e hōʻike ana he stereospecific ka pale L-Glutamine-mediated.

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Nā hōʻailona pōʻino Xi – Hoʻohaunaele
Nā Code Risk 36/37/38 – Hoʻonanea i nā maka, ʻōnaehana hanu a me ka ʻili.
Ka wehewehe palekana S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka.
S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
S27 – Wehe koke i na lole i haumia.
S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka.
WGK Kelemānia 3
HS Code 29241900

 

Hoʻolauna

ʻAʻole hiki ke hoʻoheheʻe ʻia ka isomer kūlohelohe o ka glutamine i ka methanol, ethanol, ether a me benzene.

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