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Ethyl 3-(2-((4-cyanophenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate(CAS# 211915-84-3 )

Waiwai Kemika:

ʻĀpana Molekala C27H26N6O3
Molar Mass 482.53
ʻO ka mānoanoa 1.25±0.1 g/cm3 (Wānana ʻia)
Lae hehee 149-151°C
Lae Boling 756.4±60.0 °C(Wānana ʻia)
Lae Flash 411.245°C
Ka hoʻoheheʻe DMSO (Slightly, Sonicated), Methanol (Very Slightly, Sonicated)
Puʻupuʻu mahu 0mmHg ma 25°C
Ka nana aku Paʻa
kala kala Keokeo a Pale Beige
pKa 4.21±0.10(Wānana ʻia)
Kūlana Waihona E mālama i kahi pōʻeleʻele, Inert ea, lumi wela
Hōʻike Hōʻike 1.64

Huahana Huahana

Huahana Huahana

 

Hoʻolauna

N-[[2-[[(4-cyanobenzenyl)amine]methyl]-1methyl-1H-5-benzimidazole]carbonyl]3-aminobenzoyl]N-2-pyridyl-b-alanine ethyl ester, i pōkole ʻia me N-PCBMITPAAE. ʻO kēia ka hoʻolauna ʻana i kona ʻano, hoʻohana, hoʻomākaukau a me ka ʻike palekana:

 

ʻAno maikaʻi:

Ke ʻano: paʻa ʻole a i ʻole ke aniani melemele māmā.

Solubility: Hiki ke hoʻoheheʻe ʻia ka N-PCBMITPAAE i kekahi mau mea hoʻoheheʻe organik, e like me ka dimethyl sulfoxide a me ka dichloromethane. Aneane hiki ole i ka wai.

 

E hoʻohana:

Hoʻohana maʻamau ʻia ʻo N-PCBMITPAAE i ka noiʻi synthetic ma ke kahua o ke kemika. Loaʻa iā ia kahi ʻano molekala paʻakikī a me nā pūʻulu ikaika, a hiki ke hoʻohana ʻia ma ke ʻano he reagent, catalyst a i ʻole mea hoʻohui i ka synthesis organik.

 

Hanana:

He paʻakikī ke ʻano o ka hoʻomākaukau ʻana o N-PCBMITPAAE a maʻamau e koi ʻia i kahi pane he nui. ʻO kahi ʻano hoʻomākaukau maʻamau e pili ana i kēia mau ʻanuʻu: synthesis o 4-cyanoaniline a me 1-methyl-1H-5-benzimidazole, a laila hoʻololi me ka carboatelic acid e hana i ka N-[(4-cyanobenzene)methyl]-1-methyl-1H- 5-benzimidazole-2-carboxylate. A laila, hana ia me 3-aminobenzoyl chloride e hana i ka N-[(4-cyanobenzene)methyl]-1-methyl-1H-5-benzimidazole-2-carboxylic acid 3-aminobenzoyl ester. Hoʻokumu ʻia ka huahana hope loa, N-PCBMITPAAE e ka hopena me 2-pyridyl-β-alanine ethyl ester.

 

ʻIke palekana:

ʻOi aku ka paʻakikī o ke ʻano o N-PCBMITPAAE, a pono e makaʻala i ka wā o ka hoʻohana ʻana a me ka hana. Pono e hahai ʻia nā hana hoʻokolohua kūpono a pono e mālama ʻia nā mea e mālama pono ai, e like me ke komo ʻana i nā mīkina lima pale, nā pale maka, a me nā pale maka. Pono e hoʻokaʻawale ʻia mai nā kumu hoʻāla a me nā mea oxidizing ikaika, a pono e mālama ʻia nā kūlana ventilation maikaʻi. I ka mālama ʻana a me ka mālama ʻana i ka mea kemika, e ʻoluʻolu e mālama pono iā ia i mea e pale ai i nā pōʻino.


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