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huahana

ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate(CAS# 429659-01-8)

Waiwai Kemika:

ʻĀpana Molekala C18H20N4O5
Molar Mass 372.38
ʻO ka mānoanoa 1.325±0.06 g/cm3(Wanamua)
Lae hehee 86-88 °C
Lae Boling 583.3±50.0 °C(Wānana ʻia)
Lae Flash 306.592°C
Puʻupuʻu mahu 0.001Pa ma 20-32 ℃
pKa 2.62±0.10(Wanamua)
Kūlana Waihona 2-8 ℃
Hōʻike Hōʻike 1.631

Huahana Huahana

Huahana Huahana

 

Hoʻolauna

ʻO Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl) benzoylamide) propionate, i ʻike ʻia ʻo MTT (Meta-Toluidine ortho-Toluenesulphonic acid triazine ester), he mea kemika. Loaʻa iā ia nā waiwai penei:

 

Nānā: Paʻa keʻokeʻo

Solubility: Hiki ke hoʻoheheʻe ʻia i loko o nā ʻawaʻawa, nā ketones a me ka chloroform

 

ʻO nā hoʻohana nui o MTT penei:

 

Noiʻi olaola: Hoʻohana nui ʻia ka MTT no ka hoʻoholo ʻana i ka hoʻonui ʻana o ke kelepona a me ka hiki ke ola. Hoʻololi ia i ka MTT i kahi huahana polū e hoʻoheheʻe ʻia i loko o nā cell ma o ka hoʻemi ʻana iā ia, hiki ke hoʻohana ʻia e hoʻoholo i ka ola o ke kelepona.

 

Ma keʻano laulā, hiki ke hoʻokō ʻia ke ʻano hoʻomākaukau o MTT e nā pae aʻe:

 

Hoʻopili ʻia ka Methylaniline me ka 2-nitrobenzoyl chloride e loaʻa ai ka 3-(4-methylaminobenzoyl) benzoyl chloride.

Hoʻopili ʻia ka huahana i loaʻa ma ka ʻanuʻu 1 me 2-pyridone e hana i ka 3-(4-methylaminobenzoylamide) benzoyl chloride.

Hoʻopili ʻia ka huahana i loaʻa ma ka ʻanuʻu 2 me ka ethyl 3-aminopropionate e hana i ka ethyl 3-(4-methylaminobenzoylamide) propionate.

ʻO ka huahana hope, MTT, hoʻomaʻemaʻe ʻia e ka crystallization a i ʻole nā ​​ʻano hana ʻē aʻe.

 

ʻIke Palekana: He mea ʻawaʻawa ka MTT, a pono e mālama pono i ka hoʻohana ʻana a me ka hoʻolei pono ʻana. Pono e ʻaʻahu ʻia nā mea pale kūpono e like me nā mīkina lima, nā aniani, a me nā pale keʻena hana i ka wā o ka hana. E pale i ka inhalation, pili i ka ʻili, a me ka ʻai ʻana. Ke hoʻohana a hoʻolei ʻana paha i ka ʻōpala, e hahai i nā kaʻina hana palekana kūpono, a hoʻolei koke a hoʻomaʻemaʻe i nā mea i ʻike ʻole ʻia. Inā loaʻa kekahi inhalation a pili ʻili paha, e ʻimi koke i ka lāʻau lapaʻau.


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