Fmoc-D-3-Cyclohexyl Alanine (CAS # 144701-25-7)
Pilikia a palekana
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 3 |
| NUI FLUKA BRAND F | 10 |
| HS Code | 2924 29 70 |
| Papa Hazard | HOOLAHA |
Hoʻolauna
ʻO Fmoc-D-3-Cyclohexyl Alanine (CAS # 144701-25-7), i ʻōlelo pinepine ʻia ma ke ʻano he ʻakika FMOC-D-amino, he mea hoʻohuihui. Loaʻa ia ma ka hoʻohui ʻana i kahi hui methoxycarbonyl i ka hui amino o ka fmoc-3-cyclohexyl-D-alanine.
E pili ana i nā waiwai o FMOC-D-amino acid, he paʻa a i ʻole ka hopena trace hiki ke hoʻoheheʻe ʻia i loko o kekahi mau mea hoʻoheheʻe kūlohelohe, e like me ka dimethyl sulfoxide (DMSO) a me ka methanol (MeOH). Loaʻa iā ia nā waiwai absorption UV, e hōʻike ana i ka absorption kiʻekiʻe loa ma ka laulā o 240-245 nm.
Loaʻa i ka FMOC-D-amino acid ka nui o nā noi i ka noiʻi biochemical. ʻO kekahi o ka hoʻohana maʻamau ma ke ʻano he hui pale no ka solid-phase synthetase peptides a me polypeptides, e pale ana i ka hydroxyl a i ʻole nā hui amino i ka wā synthesis. Eia kekahi, hiki ke hoʻohana ʻia no ka synthesis o nā pūhui steroid biologically active a me ka hoʻomākaukau ʻana i nā peptides a i ʻole nā protein o nā ʻano kikoʻī.
ʻO ke ala maʻamau no ka hoʻomākaukau ʻana i ka waikona FMOC-D-amino ʻo ia ka hoʻohui ʻana i ka reagent chlorinating FMOC i ka pūʻulu amino o ka fmoc-3-cyclohexyl-D-alanine, a hoʻokō i ka hopena i loko o kahi mea hoʻoheheʻe kūpono a me nā kūlana pane. A laila, hiki ke loaʻa ka huahana i makemake ʻia e nā ʻanuʻu hoʻomaʻemaʻe kūpono e like me ka wehe ʻana i ka solvent a me ka chromatography kolamu.
E pili ana i ka ʻike palekana, palekana nā ʻakika FMOC-D-amino ma lalo o nā kūlana hana maʻamau. Eia nō naʻe, pono nō e lawe i nā hana palekana o ka hale hana, e like me ke komo ʻana i nā lako pale pilikino kūpono a me ka hana ʻana i kahi ʻoihana hoʻonaʻauao maikaʻi. Eia kekahi, e like me nā kūlana kikoʻī o kēlā me kēia keʻena hana, pono e hahai ʻia nā kaʻina hana palekana kūpono a me ka mālama ʻana i ka wā o ka hoʻohana ʻana a me ka mālama ʻana.
E pili ana i nā waiwai o FMOC-D-amino acid, he paʻa a i ʻole ka hopena trace hiki ke hoʻoheheʻe ʻia i loko o kekahi mau mea hoʻoheheʻe kūlohelohe, e like me ka dimethyl sulfoxide (DMSO) a me ka methanol (MeOH). Loaʻa iā ia nā waiwai absorption UV, e hōʻike ana i ka absorption kiʻekiʻe loa ma ka laulā o 240-245 nm.
Loaʻa i ka FMOC-D-amino acid ka nui o nā noi i ka noiʻi biochemical. ʻO kekahi o ka hoʻohana maʻamau ma ke ʻano he hui pale no ka solid-phase synthetase peptides a me polypeptides, e pale ana i ka hydroxyl a i ʻole nā hui amino i ka wā synthesis. Eia kekahi, hiki ke hoʻohana ʻia no ka synthesis o nā pūhui steroid biologically active a me ka hoʻomākaukau ʻana i nā peptides a i ʻole nā protein o nā ʻano kikoʻī.
ʻO ke ala maʻamau no ka hoʻomākaukau ʻana i ka waikona FMOC-D-amino ʻo ia ka hoʻohui ʻana i ka reagent chlorinating FMOC i ka pūʻulu amino o ka fmoc-3-cyclohexyl-D-alanine, a hoʻokō i ka hopena i loko o kahi mea hoʻoheheʻe kūpono a me nā kūlana pane. A laila, hiki ke loaʻa ka huahana i makemake ʻia e nā ʻanuʻu hoʻomaʻemaʻe kūpono e like me ka wehe ʻana i ka solvent a me ka chromatography kolamu.
E pili ana i ka ʻike palekana, palekana nā ʻakika FMOC-D-amino ma lalo o nā kūlana hana maʻamau. Eia nō naʻe, pono nō e lawe i nā hana palekana o ka hale hana, e like me ke komo ʻana i nā lako pale pilikino kūpono a me ka hana ʻana i kahi ʻoihana hoʻonaʻauao maikaʻi. Eia kekahi, e like me nā kūlana kikoʻī o kēlā me kēia keʻena hana, pono e hahai ʻia nā kaʻina hana palekana kūpono a me ka mālama ʻana i ka wā o ka hoʻohana ʻana a me ka mālama ʻana.
E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou
