FMOC-D-ARG-OH (CAS# 130752-32-8)

ʻO ka Fmoc-D-arginine kahi mea hoʻohuihui me ka inoa kemika N-(9-fluoroeimelanyl) D-arginine. He paʻa keʻokeʻo keʻokeʻo, paʻa i ka mahana wela. ʻO ka Fmoc-D-arginine he amino acid me ka hana koʻikoʻi koʻikoʻi, ʻo ia ka derivative o D-arginine.

Hoʻohana nui ʻia ʻo Fmoc-D-arginine ma nā kahua o ka biochemistry a me nā lāʻau lapaʻau. Hoʻohana pinepine ʻia ia ma ke ʻano he mea hoʻomaka a i ʻole waena no ka synthesis o polypeptides a hiki ke hoʻohana ʻia i ka synthesis solid phase, synthesis chemical a me biosynthesis. Hiki ke hoʻohana ʻia ka Fmoc-D-arginine ma ke ʻano he hale kūkulu o nā peptides antimicrobial a me nā peptides bioactive no ka hoʻomohala ʻana i nā mea antibacterial, nā lāʻau lapaʻau a me nā lāʻau anticancer.

Hiki ke hoʻomākaukau ʻia ka Fmoc-D-arginine ma ka hoʻomākaukau mua ʻana i ka D-arginine, a laila e hoʻopili ʻia me ka 9-fluoroemecyl chloride e loaʻa ai ka huahana. Pono e hoʻokō ʻia nā kūlana hopena ma lalo o ka pale o ke kinoea inert, maʻamau me ka hoʻohana ʻana i ka medium kumu a me ka solvent organik. Hiki ke hana ʻia ka hoʻomākaukau ʻana e nā ʻano i loko o ka palapala a i wehewehe ʻia ma nā patent.

Pono ka ʻike palekana Fmoc-D-Arginine. He mea hoʻonāukiuki a pilikia paha a pono e hana ʻia e like me nā kaʻina hana palekana no nā kemika. E ʻaʻahu i nā lako pale pilikino kūpono e pale aku i ka pili pono ʻana me ka ʻili a me nā maka. E hōʻalo i ka hanu ʻana i ka lepo a i ʻole ke kinoea a mālama pono i ka wahi hana. Hōʻalo i ka hoʻopili ʻana me nā oxidants, nā waikawa a me nā mea ʻino ʻē aʻe i ka wā o ka mālama ʻana a me ka lawelawe ʻana e pale aku i nā hopena a i ʻole nā ​​ulia.