FMOC-D-Valine（CAS# 84624-17-9)
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 3 |
| HS Code | 2924 29 70 |
Hoʻolauna
ʻO ka fmoc-D-valine (fmoc-D-valine) he mea hoʻoheheʻe kemika i hoʻohana nui ʻia i ka peptide synthesis a me ka ʻenehana protein i ka synthesis paʻa. Loaʻa iā ia nā waiwai penei:
1. waiwai kemika: fmoc-D-valine he paʻa keʻokeʻo, me ka hydrophobic. Hiki ke hoʻoheheʻe ʻia i loko o nā mea hoʻoheheʻe kūlohelohe e like me ka dimethyl sulfoxide (DMSO) a me ka methylene chloride, akā hiki ke hoʻoheheʻe ʻia i ka wai. ʻO C21H23NO5 kāna kumu molekala a ʻo kona kaumaha mole 369.41.
2. hoʻohana: fmoc-D-valine kekahi o nā mea waiwai nui no ka synthesis o nā peptides a me nā protein, hiki ke hoʻohana ʻia no ka synthesis o nā peptides biologically active. Hoʻohana maʻamau ia i ka synthesis solid-phase e hana i nā kaulahao peptide e nā hopena condensation me nā koena amino acid ʻē aʻe. Eia kekahi, hiki ke hoʻohana ʻia e aʻo i ka synthesis o nā peptides ikaika a me ka hoʻolālā lāʻau.
3. Keʻano o ka hoʻomākaukau ʻana: ʻO ka synthesis o ka fmoc-D-valine ka mea maʻamau e hana ʻia e kahi ʻano synthesis kemika. Hoʻopili mua ʻia ʻo L-valine me ka hui pale Fmoc e pale i ka hui amino i ka hopena kemika. Hoʻopau ʻia ka pūʻulu pale Fmoc e kahi pane deprotection e hāʻawi i ka fmoc-D-valine.
4. ʻike palekana: he palekana maikaʻi ka fmoc-D-valine ma lalo o nā kūlana maʻamau o ka hoʻohana ʻana, akā pono naʻe e hoʻolohe i kēia mau mea: e pale i ka pili ʻana me ka ʻili a me nā maka, e like me ka hoʻopili ʻia ʻana, pono e holoi koke me ka wai nui, a imi i ke kokua kino; I ka wā o ka hana pono e hoʻolohe i ka meaʻai a me ka hoʻomaʻemaʻe pilikino; pono e hoʻopaʻa ʻia ka waiho ʻana, e pale i ka lā pololei a me ke ʻano haʻahaʻa. I ka hoʻohana ʻana, e ʻoluʻolu e nānā i nā ʻōlelo aʻoaʻo palekana pili a me nā pepa ʻikepili palekana waiwai (MSDS).
