Fmoc-L-glutamic acid-gamma-benzyl ester (CAS# 123639-61-2)

ʻO ka Fluorene methoxycarbonyl-L-glutamic acid-Γ-benzyl kahi mea hoʻohui i hoʻohana ʻia i ka synthesis peptide i ka synthesis solid-phase. ʻO kona ʻano:
- Ke ʻano: keʻokeʻo a ʻeleʻele melemele paʻa
- Solubility: Fmoc-L-Glu(OtBu)-OH maikaʻi ka solubility i waena o nā mea hoʻoheheʻe kūlohelohe maʻamau.

ʻO ka hoʻohana nui o Fmoc-L-Glu (OtBu)-OH he pūʻulu pale i ka peptide synthesis. I ka synthesizing peptide kaulahao, Fmoc-L-Glu(OtBu)-OH hoʻopaʻa i nā amino acids, e pale ana i kā lākou hana e kūʻē i nā hopena kikoʻī ʻole me nā reactants ʻē aʻe. Ma hope o ka pau ʻana o ka hopena, hiki ke wehe ʻia ka Fmoc-L-Glu(OtBu)-OH ma ka wehe ʻana i ka hui pale e hoʻihoʻi i ka hana o nā waikawa amino.

ʻO ka hoʻomākaukau ʻana o Fmoc-L-Glu(OtBu)-OH he mea paʻakikī a koi maʻamau i ka hoʻohana ʻana i kahi ʻano o nā ʻanuʻu o ka synthesis organik. Hoʻopili ʻia ka glutamic acid me ka bromoacetate e loaʻa ai ka ethyl glutamate. A laila, hoʻopili ʻia ka ethyl glutamate me ka benzyl alcohol e hana i ka ethyl glutamate benzyl alcohol ester. Hoʻopili ʻia ka Ethyl glutamate benzyl alcohol ester me Fmoc-Cl e hoʻohua i ka huahana i manaʻo ʻia Fmoc-L-Glu(OtBu)-OH.

ʻIke Palekana: ʻO Fmoc-L-Glu(OtBu)-OH kahi lāʻau lapaʻau a pono e hoʻohana ʻia ma lalo o ka hana palekana. E hahai i nā hana palekana o ke keʻena hana maʻamau, e like me ke komo ʻana i nā lako pale pilikino (e laʻa, nā mīkina lima lab, nā maka aniani, a me nā mea ʻē aʻe). Pono e mālama ʻia ka mea hoʻohui i loko o kahi pahu paʻa i ka ea, ma kahi mamao o ka ignition a me nā oxidants.