Fmoc-L-homophenylalanine (CAS # 132684-59-4)

Nā hōʻailona pōʻino	Xi – Hoʻohaunaele
Nā Code Risk	36/37/38 – Hoʻonanea i nā maka, ʻōnaehana hanu a me ka ʻili.
Ka wehewehe palekana	S22 – Mai hanu i ka lepo. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. S44 - S35 - Pono e hoʻolei ʻia kēia mea a me kāna ipu i kahi ala palekana. S28 – Ma hope o ka pili ʻana me ka ʻili, holoi koke me ka nui o ke kopa. S7 – Paʻa paʻa ka ipu. S4 - E haʻalele i kahi noho.
WGK Kelemānia	3
HS Code	2924 29 70
Papa Hazard	HOOLAHA

ʻO Fmoc-L-homophenylalanine kahi mea hoʻoheheʻe amino acid. Loaʻa iā ia nā waiwai penei:1. ʻAno: keʻokeʻo maʻamau a i ʻole melemele māmā a i ʻole ka pauda.
2. Solubility: Hiki ke hoʻoheheʻe ʻia i nā mea hoʻoheheʻe organik e like me dimethyl sulfoxide (DMSO) a me ka ethyl acetate (EtOAc), hiki ʻole ke hoʻoheheʻe ʻia i ka wai.
3. kumu mole: C32H29NO4.
4. kaumaha molekalale: 495.58.

ʻO ka hoʻohana nui ʻana o Fmoc-L-homophenylalanine he pūʻulu pale i ka peptide synthesis. ʻO ka Fmoc kahi pōkole no ka furoyl a me kāna mau mea i loaʻa, hiki ke pale i ka hui amino i nā waikawa amino. Ke makemake ʻia e synthesize i ke kaulahao peptide, hiki ke loaʻa ka hui amino no ka pane ʻana ma ka wehe ʻana i ka hui pale Fmoc. No laila, he kuleana koʻikoʻi ka Fmoc-L-homophenylalanine i ka hoʻomākaukau ʻana i nā lāʻau peptide a me nā molekole bioactive pili.

ʻO ke ʻano o ka hoʻomākaukau ʻana o Fmoc-L-homophenylalanine he mea paʻakikī a komo i ka hopena synthesis multi-step. ʻO kahi ʻano hoʻomākaukau maʻamau ma o ka hoʻopili ʻana i ka phenylalanine pale ʻia Fmoc me nā mea hoʻohui ʻē aʻe, e like me ke kālā azide formate (AgNO2), a ukali ʻia e ka trifluoroacetic acid treatment e hāʻawi iā Fmoc-L-homophenylalanine.

Pono e ʻike ʻia ka ʻike palekana i ka wā e hoʻohana ai i ka Fmoc-L-homophenylalanine:

1. pale aku i ka pili pono me ka ili, ka maka a me ka mucous membrane, no ka mea, he mea ia e hoonaukiuki ai i ke kino kanaka.
2. Pono ka mālama ʻana e pale i ka hoʻopili ʻana me nā oxidants ikaika a i ʻole nā ​​​​ʻakika ikaika e pale ai i nā hopena ʻino.
3. E hoʻohana i nā lako pale pilikino kūpono e like me nā mīkina lima, nā makaaniani pale a me nā ʻaʻahu hale hana i ka wā e hoʻohana ai a lawelawe ʻia.
4. Pono e ho'okō 'ia nā hana a pau ma lalo o nā kūlana ke'ena ho'ohua maika'i.

I ka hōʻuluʻulu ʻana, ʻo Fmoc-L-homophenylalanine kahi hui pale amino acid i hoʻohana maʻamau ʻia i ka peptide synthesis a he nui nā noi. I ka hoʻohana ʻana a me ka mālama ʻana i ka pūhui, pono e hoʻolohe i ka mālama ʻana a me ka mālama ʻana.