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huahana

FMOC-L-Leucine(CAS# 35661-60-0)

Waiwai Kemika:

ʻĀpana Molekala C21H23NO4
Molar Mass 353.41
ʻO ka mānoanoa 1.2107 (manaʻo koʻikoʻi)
Lae hehee 152-156°C(māmā)
Lae Boling 486.83°C (manaʻo koʻikoʻi)
Kahuli kiko'ī(α) -26 º (c=1, DMF 24 ºC)
Lae Flash 292.4°C
Ka hoʻoheheʻe DMF (Pili iki), DMSO (Pili iki)
Puʻupuʻu mahu 2.28E-13mmHg ma 25°C
Ka nana aku Paʻa
kala kala Keʻokeʻo i ke Keʻokeʻo
BRN 2178254
pKa 3.91±0.21(Wanamua)
Kūlana Waihona E mālama ʻia ma lalo o +30 ° C.
Paʻa Hygroscopic
Hōʻike Hōʻike -25 ° (C=1, DMF)
MDL MFCD00037133
Hoʻohana ʻO ka ligand o PPARγ, hoʻoulu i ka naʻau o ka insulin, akā ʻaʻole ka hoʻokaʻawale adipocyte

Huahana Huahana

Huahana Huahana

Nā hōʻailona pōʻino Xi – Hoʻohaunaele
Nā Code Risk 36/37/38 – Hoʻonanea i nā maka, ʻōnaehana hanu a me ka ʻili.
Ka wehewehe palekana S22 – Mai hanu i ka lepo.
S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka.
S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka.
S27 – Wehe koke i na lole i haumia.
S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
WGK Kelemānia 3
HS Code 2924 29 70

 

Hoʻolauna

ʻO FMOC-L-leucine kahi mea hoʻohui kino.

 

ʻAno maikaʻi:

ʻO FMOC-L-leucine he keʻokeʻo a melemele me ka hygroscopicity ikaika. Hiki ke hoʻoheheʻe ʻia i nā mea hoʻoheheʻe organik e like me ka ethanol, methanol, a me dimethylformamide, a me nā mea ʻē aʻe.

 

E hoʻohana:

Hoʻohana nui ʻia ʻo FMOC-L-leucine no ka peptide synthesis a me ka polymer synthesis i ka synthesis solid-phase. Ma ke ʻano he pūʻulu pale i ka peptide synthesis, pale ia i nā hopena kikoʻī ʻole o nā waikawa amino ʻē aʻe, e hana i ke kaʻina hana synthesis i kikoʻī a me ka maʻemaʻe kiʻekiʻe.

 

Hanana:

Hiki ke hoʻomākaukau ʻia ka FMOC-L-leucine e ka condensation o ka leucine me 9-fluhantadone. Hoʻohui ʻia ka N-acetone a me ka leucine i kahi mea hoʻoheheʻe polar, a laila ua hoʻohui mālie ʻia ʻo 9-fluhantadone i dropwise, a ma hope ua lawe ʻia ka crystallization no ka loaʻa ʻana o ka huahana.

 

ʻIke palekana:

ʻO ka FMOC-L-leucine ka mea maʻamau ʻaʻole ʻona i ke kanaka a me ke kaiapuni. Ma ke ʻano he mea hoʻohuihui, hiki ke loaʻa ka hopena hoʻonāukiuki i ka ʻili, nā maka, a me nā membrane mucous. Pono e pale ʻia ka pili lōʻihi me ka ʻili i ka wā o ka hoʻohana ʻana, a pono e mālama pono e pale aku i ka pili ʻana me nā maka a me ka inhalation o kona lepo.


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