Fmoc-L-tert-leucine (CAS # 132684-60-7)
Pilikia a palekana
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka. |
| WGK Kelemānia | 3 |
| HS Code | 29242990 |
| Papa Hazard | HOOLAHA |
Hoʻolauna:
Hoʻokomo ʻia ʻo Fmoc-L-tert-leucine (CAS # 132684-60-7), kahi waiwai amino acid derivative pono no ka peptide synthesis a me nā noi noiʻi. Hoʻolālā ʻia kēia pūhui maʻemaʻe kiʻekiʻe no nā chemists a me nā mea noiʻi e koi ana i ka pololei a me ka hilinaʻi i kā lākou hana. He ʻano pale ʻia ʻo Fmoc-L-tert-leucine o ka amino acid leucine, e hōʻike ana i kahi hui 9-fluorenylmethoxycarbonyl (Fmoc) e hiki ai ke koho i ka deprotection i ka wā o ka peptide synthesis, e lilo ia i mea waiwai nui i ke kahua o ka kemika organik.
Me kona hoʻolālā kū hoʻokahi, hāʻawi ʻo Fmoc-L-tert-leucine i hoʻonui i ka paʻa a me ka solubility, e hōʻoiaʻiʻo ana i ka hana maikaʻi loa i nā hopena kemika. Hoʻohana nui ʻia kēia pūhui i ka solid-phase peptide synthesis (SPPS), kahi e hiki ke wehe maʻalahi i ka hui pale Fmoc ma lalo o nā kūlana maʻalahi, e hoʻomaʻamaʻa i ka hoʻohui pū ʻana o nā waikawa amino e kūkulu i nā kaulahao peptide paʻakikī. Hāʻawi kāna kaulahao ʻaoʻao tert-butyl i ka steric hindrance, hiki ke lilo i mea maikaʻi i ka mālama ʻana i ka conformation o nā peptides, i ka hopena i kā lākou hana olaola.
Hana ʻia kā mākou Fmoc-L-tert-leucine ma lalo o nā ana hoʻomalu maikaʻi koʻikoʻi, e hōʻoia ana e hoʻokō i nā kūlana kiʻekiʻe loa no ka maʻemaʻe a me ke kūpaʻa. Loaʻa ia ma nā ʻano nui e kūpono i kāu mau noiʻi noiʻi kikoʻī, inā ʻoe e hana ana ma nā papahana liʻiliʻi a i ʻole ka peptide synthesis nui.
Ma waho aʻe o kāna mau noi i ka peptide synthesis, ʻo Fmoc-L-tert-leucine kekahi mea waiwai nui i ka hoʻomohala ʻana i nā lāʻau lapaʻau, bioconjugates, a me nā pūhui bioactive ʻē aʻe. ʻO kāna versatility a me ka hilinaʻi e lilo ia i mea e pono ai no kēlā me kēia keʻena keʻena e pili ana i ka kemika peptide.
E hoʻokiʻekiʻe i kāu noiʻi a me ka hana synthesis me Fmoc-L-tert-leucine (CAS # 132684-60-7) - ke koho maikaʻi loa no ka poʻe chemists e ʻimi nei i ka maikaʻi a me ka hana i kā lākou hana peptide synthesis.
