Ftorafur（CAS#17902-23-7）
| Nā hōʻailona pōʻino | T – ʻAʻohe |
| Nā Code Risk | 23/24/25 – He mea ʻawaʻawa ma ka inhalation, pili me ka ʻili a inā ale ʻia. |
| Ka wehewehe palekana | S22 – Mai hanu i ka lepo. S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. S45 – Inā loaʻa ka pōʻino a i ʻole ka maikaʻi ʻole, e ʻimi koke i ka ʻōlelo aʻo kino (e hōʻike i ka lepili inā hiki.) |
| UN ID | UN 2811 6.1/PG 2 |
| WGK Kelemānia | 3 |
| RTECS | YR0450000 |
| HS Code | 29349990 |
| Papa Hazard | 6.1 |
| Hui Pūʻulu | II |
| Kaʻawaʻawa | LD50 i nāʻiole (mg/kg): 900 waha (3 lā) (Yasumoto); 750 ip (FR 1574684), hōʻike pū ʻia ʻo 1150 ip (Smart) |
Hoʻolauna
ʻO ka Trifluoromethylation kahi hopena kemika organik kahi e hiki ai ke hoʻokomo ʻia nā pūʻulu trifluoromethyl i loko o nā molekala organik me ka hoʻohana ʻana i nā reagents tegafluor e like me TMSCF3.
Nā waiwai o tegafluor:
- ʻO Tegafluor kahi hopena hoʻololi hui koʻikoʻi, hiki iā ia ke hoʻolauna i nā pūʻulu trifluoromethyl me kahi ʻano electron density e hoʻololi i nā waiwai kino a me nā molekala.
- Loaʻa i nā hui Trifluoromethyl ka huki electron ikaika, hiki ke hoʻonui i ka electrophilicity o ka mole a me ka solubility o ka solvent.
- ʻO nā huahana o ka pane tegafluor ka mea maʻamau paʻa a me ka hana biologically.
Nā hoʻohana o ka tegafluor:
- Ma ke kahua o ka ʻepekema waiwai, hiki i ka tegafluor ke hoʻololi i nā waiwai o ka ʻili o nā mea, hoʻonui i ko lākou kūpaʻa a me ka pale ʻana i ka wā.
ʻO ke ʻano o ka hoʻomākaukau ʻana o tegafluor:
- Hoʻohana pinepine ʻia nā reagent tegafluor: TMSCF3, Ruppert-Prakash reagent, etc.
- Hoʻohana mau ʻia nā hopena Tegafluor i loko o ka lewa inert, me ka hoʻohana ʻana i kahi mea hoʻoheheʻe inert (e laʻa, methylene chloride, chloroform) ma ke ʻano he ʻano hana.
- Pono nā kūlana hoʻololi i ka wela o ka hopena a me ka manawa ʻoi aku ka lōʻihi, a koi pinepine i ka hoʻohui ʻana i kahi catalyst (e laʻa, copper catalyst).
ʻIke palekana ma tegafur:
- He mea ʻawaʻawa a ʻino nā mea hoʻohui ʻo Tegafluor, a pono e mālama pono i ka wā e lawelawe ai.
- ʻO nā kinoea (e laʻa me ka hydrogen fluoride) i hana ʻia i ka wā o ka hopena he mea pōʻino nō hoʻi a pono e hana ʻia ma lalo o nā kūlana ea.
- Pono e mālama ʻia e pale aku i ka pili ʻana me ka wai a i ʻole ka haʻahaʻa i ka wā o ka hana e pale aku i nā hopena kemika hiki ʻole ke hoʻololi.
- Pono nā reactants a me nā huahana ma lalo o nā kūlana hoʻohālikelike tegafluor i ka mālama kūpono a me ka hoʻolei ʻōpala.
