L-3-Aminoisobutyric acid（CAS# 4249-19-8)

Hoʻolauna

ʻO Sb-aminoisobutyric acid (S-β-aminoisobutyric acid) he amino acid me kahi ʻano kikoʻī. He ʻakika amino kūlohelohe ia me kahi ʻano mole o C4H9NO2 a me ke kaumaha molekala o 103.12g/mol.

ʻO ka waikona Sb-aminoisobutyric kekahi o nā stereoisomers ʻelua, a ua mau kona hoʻonohonoho stereo ma ke ʻano L. He pauda crystalline keʻokeʻo, hiki ke hoʻoheheʻe ʻia i ka wai a me ka waiʻona. Paʻa ka hui i ka ea akā paʻa i ka wela a me ka māmā.

He nui nā hana physiological koʻikoʻi ʻo Sb-aminoisobutyric acid i loko o ka vivo, me ka metabolism protein, ka hoʻoponopono immune a me ka hopena i ka hana o ka lolo. Hiki ke hoʻohana ʻia e like me ka chiral charged a me ka fatty acid oxidase intracellular carrier.

Hoʻohana nui ʻia ka Sb-aminoisobutyric acid i ka lāʻau lapaʻau no nā lāʻau synthetic, anti-cancer therapy a me ka noiʻi biochemical. Hiki ke hoʻohana ʻia e aʻo i ka hana o nā protein a me nā enzymes, ke ʻano o nā protein a me nā waikawa nucleic, a me ka synthesize i nā antibiotics, analgesics a me nā pūhui bioactive ʻē aʻe.

Hiki ke hoʻohui ʻia a unuhi ʻia nā ʻano hana no ka hoʻomākaukau ʻana i ka waikawa Sb-aminoisobutyric mai nā kumu kūlohelohe. ʻO kekahi ʻano hana synthetic maʻamau ma ka hoʻohui ʻana o isovaleraldehyde. ʻO ka unuhi ʻana mai nā kumu kūlohelohe maʻamau ka hopena mai nā metabolites o kekahi mau huakini a i ʻole nā ​​​​hani.

E pili ana i ka ʻike palekana, ʻo ka Sb-aminoisobutyric acid ka mea maʻamau i manaʻo ʻia he palekana i ka wā o ka hoʻohana ʻana i nā ʻoihana a me nā hana ʻoihana. Eia nō naʻe, he kemika nō ia a pono e hoʻokō ʻia i nā hana palekana keʻena hana kūpono. I ka wā e ʻike ʻia ai, pono e hana i nā hana pale kūpono, e like me ke komo ʻana i nā mīkina lima, nā maka maka maka a me nā lole pale. Inā loaʻa ka pilikia a i ʻole ka ʻai ʻana, pono e ʻimi koke ʻia ka lāʻau lapaʻau.