L-Fmoc-Aspartic acid alpha-tert-butyl ester (CAS# 129460-09-9)

ʻO ka Fluorenylmethoxycarbonyl-aspartate-l-tert-butyl ester (Fmoc-Asp(tBu)-OH) he hui pale maʻamau i hoʻohana ʻia no ka waikawa aspartic. ʻO kēia ka wehewehe ʻana o kona ʻano, hoʻohana, hana a me ka ʻike palekana:

ʻAno:
-Ke kimeka: C26H27NO6
-Molecular kaumaha: 449.49g/mol
-Ke ʻano: Paʻa keʻokeʻo keʻokeʻo
-Ka helu hoohehee: 205-207°C

E hoʻohana:
- Hoʻohana pinepine ʻia ʻo Fmoc-Asp(tBu)-OH i ka peptide synthesis i ka synthesis paʻa paʻa ma ke ʻano he hui pale aspartic acid.
-Hiki iā ia ke hana i nā kaulahao peptide ma ka hoʻokomo ʻana i nā koena aspartic acid i loko o ke kaʻina peptide synthetic ma o ka synthesis paʻa.

Kaʻina hoʻomākaukau:
- Hiki ke loaʻa iā Fmoc-Asp(tBu)-OH ma ka hana ʻana i ka isopropyl acetate a i ʻole ka sodium hydroxide me Fmoc-Asp(tBu)-OH.

ʻIke palekana:
- Hoʻohana nui ʻia ʻo Fmoc-Asp(tBu)-OH i ka ʻoihana a me nā hale hana, a ua manaʻo ʻia he mea palekana.
- akā, pono e hoʻolohe i kona ʻona a me ka huhū.
-I ka lawelawe ʻana iā ia, e ʻaʻahu i nā mea pale kūpono, e like me nā mīkina lima a me nā maka aniani, e pale aku i ka pili ʻana me ka ʻili a me nā maka.
-I ka mālama ʻana a me ka mālama ʻana, ʻōlelo ʻia e mālama i kahi maloʻo a maloʻo, kahi mamao mai ke ahi a me nā mea hoʻoheheʻe.

E ʻoluʻolu e mālama pono i ka palekana o nā kemika. Pono e hoʻokō ʻia nā hoʻokolohua e like me nā alakaʻi hana palekana a me ka hoʻolei ʻōpala e like me nā lula pili.