Metadoxine（CAS# 74536-44-0)

Waiwai Kemika:

ʻĀpana Molekala	C8H11NO3.C5H7NO3
Molar Mass	298.293
Lae hehee	102-104°C
Ka hoʻoheheʻe	DMSO (Lili iki), Methanol (Lili iki)
Ka nana aku	Paʻa
kala kala	Keʻokeʻo i Melemele Māmā
Kūlana Waihona	Hoʻopaʻa ʻia i kahi maloʻo, 2-8 ° C
Hoʻohana	Ka hoʻoholo ʻana o ka ʻike e HPLC
Haʻawina in vitro	ʻO ka lāʻau lapaʻau Metadoxine i ka manawa like e kāohi ai i ka hoʻokaʻawale adipogenic ma ke ʻano i hilinaʻi ʻia. Pono ka lāʻau metadoxine mai ka lā 4 a hiki i ka lā 8 no ka pale ʻana i ka ʻokoʻa preadipocyte i hoʻokomo ʻia e MDI. Kāohi ka Metadoxine i ka pau ʻana o ka glutathione a me ka hoʻonui ʻana i ka pōʻino o ka lipid peroxidation i hoʻokumu ʻia e ka ethanol a me ka acetaldehyde i nā cell HepG2. I loko o nā pūnaewele stellate hepatic, pale ʻo Metadoxine i ka piʻi ʻana o ka collagen a me ka huna ʻana o TNF-α ma muli o ka acetaldehyde. No laila, hiki i ka Metadoxine ke hoʻohana i ka pale ʻana i ka pōʻino i hana ʻia i ka wā mua o ka maʻi ate ʻawaʻawa e like me ka pale ʻana i ka redox imbalance o nā hepatocytes a pale i ka TNF-α induction, kekahi o nā hanana mua loa i ka pōʻino hepatic.

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Huahana Huahana

Hoʻolauna

ʻO ka metadoxin, i kapa ʻia ʻo N, N-dimethylformamide, he wai kala ʻole. Penei kona mau waiwai.

Nā waiwai kino: He wai waihoʻoluʻu ʻole ka metadoxine me ka ʻala ʻala, ʻoluʻolu ma ka lumi wela, hiki ke hui pū me ka wai a me nā mea hoʻoheheʻe kūlohelohe maʻamau.

Nā waiwai kemika: ʻO ka metadoxine he mea hoʻohaʻahaʻa loa i hiki ke hoʻoheheʻe ʻia e ka sodium hydroxide a i ʻole ka sodium carbonate solution e hana i ka formamide a me ka methanol.

Ke hoʻohana nei i ka metaxacin:

Catalyst: Hiki ke hoʻohana ʻia ka metadoxine ma ke ʻano he mea lawe no nā mea hoʻoheheʻe metala, a hoʻohana ʻia no ka hoʻoulu ʻana i ka hopena formylation o nā amine i ka synthesis organik.

Solvents: Hoʻohana nui ʻia ka metadoxine ma ke ʻano he solvent i ka synthesis organik, e like me ka dissolving metala complexes, polymers, a me nā mea waena no nā hopena catalytic.

Ke ala hoʻomākaukau: Loaʻa ka hoʻomākaukau ʻana o ka metadoxine ma ka hopena o ka formamidine a me ka waikawa formic.

ʻIke palekana: ʻO ka Metaxacin he mea hoʻonāukiuki a hoʻomāinoino, a he hopena hoʻonāukiuki i ka ʻili, nā maka a me nā membrane mucous. Pono e mālama ʻia e pale aku i ka pili pono ʻana me ka ʻili a me nā maka, a pono e hoʻohana i nā mīkina lima pale a me nā maka aniani inā pono. Pono e noʻonoʻo i ka ea i ka wā e hoʻohana ai i mea e pale ai i ka hoʻohu ʻana i kāna mau mahu. ʻO ka Meltadoxine kahi mea hiki ke hoʻopau ʻia a pono e mālama ʻia mai nā lapalapa ākea a me nā kumu wela kiʻekiʻe.

Mua: L-Aspartic acid benzyl ester（CAS# 7362-93-8)

Aʻe: 1-Isopropoxy-1 1 2 2-tetrafluoroethane （CAS# 757-11-9)

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