Methoxymethyl triphenylphosphonium chloride（CAS# 4009-98-7)

Hoʻohana

Hoʻohana ʻia (Methoxymethyl) triphenylphosphorus chloride e synthesize i ka cefaltacin, kahi lāʻau antiviral a anti-tumor. Hoʻohana ʻia e synthesize i kahi ʻāpana o ka paclitaxel.

Hoʻomākaukau

He ala no ka synthesizing (methoxymethyl) triphenylphosphorus chloride, e pili ana i kēia mau ʻanuʻu: ma lalo o ka pale o ka nitrogen, hoʻohui i 50mL o anhydrous acetone i loko o kahi reactor, a laila hoʻohui i 32g o triphenylphosphine, hoʻoulu a hoʻonui i ka mahana i 37 ° C, mālama i kahi mahana mau. , hoʻohui i 20g o ka methyl chloromethyl ether i ka reactor, a laila e pane ana ma 37 ° C no 3h, e hoʻokiʻekiʻe mālie i ka mahana i 47 ° C ma ka wikiwiki o 1 ° C / min, ua hoʻomau ka hopena no 3h, ua hoʻopauʻia ka hopena, a ua loaʻa iā 37.0g (methoxymethyl) triphenylphosphorus chloride ma ka kānana. , anhydric ether holoi a maloʻo me ka hua o 88.5%.