N-Boc-D-tert-leucinol (CAS # 142618-92-6)
N-Boc-D-tert-leucinol (CAS # 142618-92-6) hoʻolauna
ʻO BOC-D-tert Leucinol kahi mea hoʻohuihui. He paʻa keʻokeʻo ia me kahi ʻano kristal orthorhombic. ʻO kēia pūhui kahi ʻano pale o ka amino acid D-tert-leucine maoli.
Hoʻohana pinepine ʻia ka BOC-D tert leucine i ka synthesis o nā peptides a me nā protein. Ma ke ʻano he pūʻulu pale amino, hiki iā ia ke pale i nā pūʻulu reactive ma nā kaulahao ʻaoʻao o nā amino acids, a hiki ke hoʻokuʻu i nā waikawa amino ma ka deprotection inā pono. Hana kēia i ka waiʻona leucine tertiary BOC-D i mea koʻikoʻi no ka synthesizing peptides.
ʻO ke ala nui no ka hana ʻana i ka BOC-D-tert-leucine ma o ka hopena pale o D-tert-leucine. ʻO ke ʻano hana maʻamau, ʻo ia ka pane ʻana i ka D-tertiary brilliant amine alcohol me BOC-ONH2 (BOC hydrazide) ma lalo o nā kūlana alkaline no ka loaʻa ʻana o BOC-D-tertiary brilliant amine alcohol.
Loaʻa paha nā hopena hoʻonāukiuki i ka maka, ka ʻili, a me ka ʻōnaehana hanu. Pono e noʻonoʻo i ka hoʻohana ʻana i nā mīkina lima pale, nā makaaniani, a me nā pale alo i ka wā e hoʻopili ai e pale aku ai i ka ʻike lōʻihi. E hōʻalo i ka hanu ʻana i ka lepo a i ʻole ka mahu a mālama i kahi kaiapuni hana maikaʻi. Inā komo hewa a inhaled paha, e ʻimi koke i ka lāʻau lapaʻau. Ma mua o ka hoʻohana ʻana, e heluhelu pono i ka manual palekana huahana a hana ma lalo o ke alakaʻi a nā limahana akamai.