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N-Boc-trans-4-Hydroxy-L-proline methyl ester (CAS# 74844-91-0)

Waiwai Kemika:

ʻĀpana Molekala C11H19NO5
Molar Mass 245.27
ʻO ka mānoanoa 1.216±0.06 g/cm3(Wānana ʻia)
Lae hehee 92-96 °C (māmā)
Lae Boling 132°C/0.05mmHg(māmā)
Kahuli kiko'ī(α) -65 º (c=1 CHCL3)
Lae Flash 156.55°C
Ka hoʻoheheʻe Hiki ke hoʻoheheʻe ʻia i loko o ka chloroform, dichloromethane a me ka ethyl acetate.
Puʻupuʻu mahu 0mmHg ma 25°C
Ka nana aku Crystal
kala kala Keʻokeʻo i ka beige māmā
pKa 14.27±0.40(Wanamua)
Kūlana Waihona E mālama ma kahi pouli, Hoʻopaʻa ʻia i kahi maloʻo, Ke ana wela o ka lumi
Hōʻike Hōʻike 1.501
MDL MFCD00076981

Huahana Huahana

Huahana Huahana

Nā hōʻailona pōʻino Xn – Poino
Nā Code Risk R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia.
R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili.
Ka wehewehe palekana S24/25 – Hōʻalo i ka pili ʻana me ka ʻili a me nā maka.
S36 – E komo i nā lole pale kūpono.
S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino.
WGK Kelemānia 3
HS Code 29339900
Papa Hazard HOOLAHA

 

Hoʻolauna

N-BOC-trans-4-hydroxy-L-proline methyl ester, inoa piha N-tert-butoxycarbonyl-trans-4-hydroxy-L-proline methyl ester, he mea hoʻohuihui.

 

ʻAno maikaʻi:

ʻO N-BOC-trans-4-hydroxy-L-proline methyl ester he paʻa keʻokeʻo keʻokeʻo.

 

E hoʻohana:

Hoʻohana mau ʻia ka N-BOC-trans-4-hydroxy-L-proline methyl ester ma ke ʻano he pūʻulu pale amino acid i loko o ke kemika synthesis organik. Hiki ke hoʻohana ʻia ma ke ʻano he pūʻulu pale pono e pale i nā pūʻulu hana hydroxyl i nā waikawa amino e pale ai i nā hopena makemake ʻole i ka synthesis.

 

Hanana:

ʻO ka hoʻomākaukau ʻana o ka N-BOC-trans-4-hydroxy-L-proline methyl ester e loaʻa pinepine ʻia ma ka hana ʻana i ka N-BOC-4-hydroxy-L-proline me ka methanol. Hoʻopili ʻia ka N-BOC-4-hydroxy-L-proline me kahi mea hoʻoulu (e like me DCC a i ʻole DIC) e hana i kahi ester i hoʻāla ʻia, a laila hoʻohui ʻia ka methanol e hana pū me ia e hana ai i ka N-BOC-trans-4-hydroxy- L-proline methyl ester. Loaʻa ka huahana i hoʻopaʻa ʻia e ka crystallization a i ʻole nā ​​​​ʻano hoʻokaʻawale a hoʻomaʻemaʻe ʻē aʻe.

 

ʻIke palekana: I ka wā e pili ana i ka synthesis kemika, pono e loaʻa i ka hoʻohana ʻana i nā mea hana a me nā kūlana hoʻokolohua e like me ka ʻike loea. Ma nā hana hoʻokolohua, pono e mālama ʻia e pale aku i ka hoʻopili pololei ʻana me ka ʻili a me nā maka, a me ka mālama ʻana i ka ventila maikaʻi. Inā loaʻa iā ʻoe kekahi pilikia kino a i ʻole nā ​​hopena ʻino ʻē aʻe, pono ʻoe e ʻimi koke i ka lāʻau lapaʻau.


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