N-Carbobenzyloxy-L-serine (CAS # 1145-80-8)
ʻO Cbz-L-serine kahi mea hoʻohuihui nona ka inoa kemika ʻo N-bismethylaminomethyl-2-piperazine-L-serine. ʻO kēia ka hoʻolauna ʻana i nā waiwai, hoʻohana, nā ʻano hoʻomākaukau a me ka ʻike palekana o Cbz-L-serine:
Pono: ʻO Cbz-L-serine kahi paʻa, keʻokeʻo keʻokeʻo a i ʻole ka pauka crystalline i ka lumi wela.
He mea hoʻomaka koʻikoʻi ia no ka synthesis o nā pūhui peptide, a hiki ke kiʻi ʻia ka peptide target ma o ka deprotecting group reaction.
ʻAno: ʻO ke ʻano hana synthesis o Cbz-L-serine ka mea maʻamau e hoʻohuli i ka L-serine i loko o ka acid methyl ester e like me ka hopena, a laila e hana me ka N-dimethylcarbamate keu ma lalo o nā kūlana alkaline.
ʻIke palekana: ʻO Cbz-L-serine maʻamau ka palekana no ka hoʻohana ʻana ma lalo o nā kūlana lab pono. Hiki iā ia ke hoʻonāukiuki i ka maka, ka ʻili, a me ka ʻōpū hanu. Pono e ʻaʻahu ʻia nā mea pale ponoʻī e like me nā goggles, nā mīkina lima, a me nā lole pale i ka wā o ka hana. Pono e mālama ʻia ma kahi maloʻo a me ka ʻoluʻolu e pale aku i ka hoʻopili ʻana me nā oxidants a me nā waikawa ikaika. Pono e mālama ʻia nā kaʻina hana palekana pili i ka wā e hoʻohana ai, a pono e hahai ʻia nā kaʻina hana hoʻolei kūpono a me ka hoʻolei ʻana.
