N-Cbz-D-Tryptophan（CAS# 2279-15-4)

Hoʻolauna

ʻO N(^ a)-Benzyloxycarbonyl-D-tryptophan(N(^ a)-Benzyloxycarbonyl-D-tryptophan) he mea kemika, ʻike ʻia ʻo CBZ-D-Trp. ʻO kēia ka wehewehe ʻana o kona ʻano, hoʻohana, hana a me ka ʻike palekana:

ʻAno:

N(^ a)-Benzyloxycarbonyl-D-tryptophan he paʻa keʻokeʻo a melemele. He kūpaʻa ma ka lumi wela a hiki ke mālama ʻia no ka manawa lōʻihi ma lalo o nā kūlana anhydrous. ʻAʻole hiki ke hoʻoheheʻe ʻia i ka wai, akā hiki ke hoʻoheheʻe ʻia i kekahi mau mea hoʻoheheʻe kūlohelohe e like me ka methanol a me ka dimethyl sulfoxide.

E hoʻohana:

Hoʻohana pinepine ʻia ʻo N(^ a)-Benzyloxycarbonyl-D-tryptophan ma ke ʻano he pale i nā pūʻulu i ka synthesis organik, ʻoi aku hoʻi i ka synthesis peptide kemika. ʻO kāna hoʻohana nui ʻana ma ke ʻano he derivative o nā amino acids no ka synthesis o nā modules kikoʻī i ka polypeptide a i ʻole nā ​​kaulahao protein. Hiki iā ia ke hana nui i ka synthesis o nā lāʻau hou ma kēia ʻano.

Hanana:

ʻO ka hoʻomākaukau ʻana o N(^ a)-Benzyloxycarbonyl-D-tryptophan ka mea maʻamau e hana ʻia e ka synthesis kemika. ʻO ka mua, hoʻololi ʻia ka waiʻona benzyl a me carbon dioxide e hana i ka waikawa benzyloxycarboxylic, a laila esterified ka amino acid tryptophan a me benzyloxycarboxylic acid e loaʻa ai ka huahana CBZ-D-Trp. Pono ka hopena i ke kōkua o kekahi mau mea hoʻoheheʻe organik a me nā mea hoʻoheheʻe.

ʻIke palekana:

N(^ a)-Benzyloxycarbonyl-D-tryptophan i kaupalena 'ike palekana, akā ma muli o ka 'ike i loa'a, ua mana'o 'ia he mea 'awa'awa. Loaʻa paha nā hopena olakino maikaʻi ʻole ka hoʻolaha lōʻihi a i ʻole ka hoʻolaha nui ʻana. No laila, pono e lawe ʻia nā hana palekana kūpono i ka wā e hoʻohana ai, mālama a mālama ʻana i kēia pūhui, me ka hoʻohana ʻana i nā lako pale pilikino kūpono a me ka lawelawe ʻana i kahi kaiapuni maikaʻi. I ka manawa like, pono e hahai i nā kaʻina hana palekana kūpono a me nā ʻano hoʻokuʻu.

E ʻoluʻolu, ʻo kēia ʻatikala he hiʻohiʻona wale nō o ka pūhui i nīnau ʻia, a pono e hoʻokō ʻia ka noi kikoʻī a me ka loiloi pilikia i loko o kahi kaiapuni kikoʻī. Ma mua o ka hoʻohana ʻana i kekahi mea kemika, e ʻoluʻolu e aʻo i ka ʻike pili i nā kikoʻī a nīnau mua i kahi loea.