N-Cbz-L-Leucine（CAS# 2018-66-8)
Pilikia a palekana
| Nā hōʻailona pōʻino | Xn – Poino |
| Nā Code Risk | R10 – Hiki ke ahi R20/22 – He pōʻino ma ka inhalation a inā ale ʻia. R37/38 – Hoʻonanea i ka ʻōnaehana hanu a me ka ʻili. R40 - Nā hōʻike liʻiliʻi o ka hopena carcinogenic R41 – Ka pilikia o ka poino nui i na maka R36/37/38 – Hoʻonanea i ka maka, ka ʻōpū hanu a me ka ʻili. R20/21/22 – He pōʻino ma ka inhalation, pili me ka ʻili a inā ale ʻia. R67 – Hiki i ka mahu ke kumu i ka hiamoe a me ka poni R63 – Hiki ke pilikia i ke keiki hānau ʻole R19 - Hiki ke hana i nā peroxide pahū |
| Ka wehewehe palekana | S16 – E hoʻokaʻawale i nā kumu hoʻā. S26 – Inā pili me nā maka, e holoi koke me ka wai nui a e ʻimi i ka ʻōlelo aʻo kino. S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. S45 – Inā loaʻa ka pōʻino a i ʻole ka maikaʻi ʻole, e ʻimi koke i ka ʻōlelo aʻo kino (e hōʻike i ka lepili inā hiki.) S36 – E komo i nā lole pale kūpono. S36/37 – E hoʻohana i nā lole pale kūpono a me nā mīkina lima. S60 - Pono e hoʻolei ʻia kēia mea a me kāna pahu ma ke ʻano he ʻōpala weliweli. |
| UN ID | UN 1993 3/PG 3 |
| WGK Kelemānia | 3 |
| RTECS | OH2921000 |
| HS Code | 29242990 |
N-Cbz-L-Leucine（CAS# 2018-66-8) hoʻolauna
ʻO Cbz-L-leucine, ka inoa piha o Boc-L-leucine (Boc kū no ka dibutoxycarbonyl protecting group), he amino acid derivative. ʻO kēia ka hoʻolauna ʻana i kona ʻano, hoʻohana, hana hana a me ka ʻike palekana:
ʻAno maikaʻi:
- Ke ʻano: Paʻa keʻokeʻo keʻokeʻo
- Hiki ke hoʻoheheʻe ʻia: Hiki ke hoʻoheheʻe ʻia i ka ethanol, dimethylformamide (DMF) a me ka dichloromethane
E hoʻohana:
- ʻO CBZ-L-Leucine kahi hui pale amino acid i hoʻohana mau ʻia e pale i ka pūʻulu hydroxyl o ka leucine i ka wā o ka synthesis o nā peptides e pale aku ai i ka hana ʻana me nā mea hoʻohālikelike ʻē aʻe. I ka peptide synthesis kahi e hoʻokomo ʻia ai nā koena leucine he nui, hiki ke hoʻohana ʻia ʻo Cbz-L-leucine e pale i ka pūʻulu hydroxyl o leucine no nā kaʻina hana synthesis ma hope.
- He ʻakika amino koʻikoʻi ʻo Leucine e pāʻani ana i ka hana koʻikoʻi i ke ʻano o ka protein a me ka hana.
Hanana:
- Loaʻa maʻamau ka hoʻomākaukau ʻana o Cbz-L-leucine ma ka hopena o ka leucine me Boc-OSu (Boc—N-nitrocarbonyl-L-leucine). I ka hopena, hana ʻo Boc-OSu ma ke ʻano he mea hoʻolauna o ka pūʻulu pale a loaʻa i ka hopena esterification me ka leucine e hoʻohua i ka Cbz-L-leucine.
ʻIke palekana:
- He kemika ka Cbz-L-leucine a pono e mālama pono ʻia mai ka ʻā a me nā mea ʻona.
- I ka wā o ka hoʻohana ʻana, e pale i ka hanu ʻana i kona lepo a i ʻole e pili ana i ka ʻili a me nā maka.
- E hahai i nā hana palekana kūpono i ka wā e lawelawe ai a mālama ʻia, a e hoʻokomo i nā lako pale pilikino kūpono e like me nā mīkina lima lab a me ka pale maka.
