N-Fmoc-N'-trityl-L-histidine (CAS# 109425-51-6)

Hoʻokomo ʻia ʻo N-Fmoc-N'-trityl-L-histidine (CAS # 109425-51-6), he poloka hale no ka peptide synthesis i hoʻolālā ʻia e hoʻokiʻekiʻe i kāu mau noiʻi a me nā papahana hoʻomohala. ʻO kēia pūhui hoʻomaʻemaʻe kiʻekiʻe he mea pono ia no nā chemists a me nā biochemists e nānā ana e hana i nā peptides paʻakikī me ka pololei a me ka pono.

ʻO N-Fmoc-N'-trityl-L-histidine kahi ʻano pale o ka amino acid histidine, e hōʻike ana i nā pūʻulu pale ʻelua Fmoc (9-fluorenylmethoxycarbonyl) a me trityl. He mea koʻikoʻi kēia mau pūʻulu pale no ka hōʻoia ʻana i ke kūpaʻa a me ka hana hou o ka waikawa amino i ka wā o ke kaʻina hana synthesis. Hāʻawi ka hui Fmoc i ka pale maʻalahi ma lalo o nā kūlana maʻalahi, ʻoiai ʻo ka hui trityl e hāʻawi i ka pale hou aku i nā ʻaoʻao ʻaoʻao i makemake ʻole ʻia, e hana i kēia pūhui kūpono no ka solid-phase peptide synthesis (SPPS).

Me ka molecular formula o C30H31N3O2 a me ka molecular paona o 469.59 g/mol, N-Fmoc-N'-trityl-L-histidine hōʻike i ka solubility maikaʻi loa i nā mea hoʻoheheʻe organik maʻamau, e hoʻomaʻamaʻa i kona hoʻohui ʻia i loko o nā protocol synthetic like ʻole. ʻAʻole hoʻomaikaʻi wale kāna ʻano hana i ka paʻa o nā peptides hopena akā kōkua pū kekahi i kā lākou hana olaola, e lilo ia i waiwai waiwai i ka ʻike ʻana a me ka hoʻomohala ʻana i ka lāʻau.

Inā ʻoe e hana ana i nā peptides therapeutic, noiʻi i ka biology molecular, a i ʻole e ʻimi ana i nā ala hou i ka biochemistry, ʻo N-Fmoc-N'-trityl-L-histidine ka koho kūpono no kāu mau pono synthesis. Hana ʻia kā mākou huahana ma lalo o nā ana hoʻomalu maikaʻi e hōʻoia i ka pae kiʻekiʻe o ka maʻemaʻe a me ke kūpaʻa, e ʻae iā ʻoe e nānā pono i kāu noiʻi me ka hilinaʻi.

Wehe i ka hiki o kāu mau hana peptide synthesis me N-Fmoc-N'-trityl-L-histidine. E ʻike i ka ʻokoʻa i hiki i nā reagents kiʻekiʻe ke hana i kāu keʻena hana i kēia lā!