N-tert-Butoxacarbonyl-O-benzyl-L-threonine (CAS # 15260-10-3)

Hoʻolauna
ʻO N-Boc-O-benzyl-L-threonine kahi mea hoʻohuihui. ʻO kēia ka hoʻolauna ʻana i kona ʻano, hoʻohana, hana hana a me ka ʻike palekana:

ʻAno maikaʻi:
ʻO N-Boc-O-benzyl-L-threonine he keʻokeʻo a keʻokeʻo keʻokeʻo keʻokeʻo paʻa, hiki ke hoʻoheheʻe ʻia i nā mea hoʻoheheʻe kūlohelohe maʻamau e like me ka ethanol, dimethylformamide, chloroform, etc.

E hoʻohana:
ʻO N-Boc-O-benzyl-L-threonine kahi mea koʻikoʻi i waena o ka synthesis organik a hoʻohana mau ʻia i ka synthesis o nā peptides a me nā protein. Hiki ke hoʻohana ʻia ma ke ʻano he hui pale i ka synthesis solid-phase, ka wai-phase synthesis a me ka ethanolamine-mediated synthesis e pale i ka ʻaoʻao o ka threonine i ke kaʻina hana, i mea e hoʻomaikaʻi ai i ka koho a me ka hopena o ka hopena.

Hanana:
Hana ʻia ka hoʻomākaukau ʻana o N-Boc-O-benzyl-L-threonine e ka synthesis kemika. Hoʻopili ʻia ʻo Threonine me N-tert-butoxycarbonyl (Boc-O-benzyl) a ua hoʻohui ʻia nā mea hoʻoulu e like me N,N-diisopropylethylamine (DIPEA) a i ʻole carbodiimide (DCC). Ma hope o ka hopena, loaʻa ka N-Boc-O-benzyl-L-threonine.

ʻIke palekana:
Loaʻa i ka N-Boc-O-benzyl-L-threonine kahi kūlana palekana kiʻekiʻe, akā ma ke ʻano he hui organik, pono e hoʻomanaʻo ʻia kēia mau mea palekana: pale i ka pili ʻana me ka ʻili, nā maka a me ka ʻōnaehana hanu; E hoʻohana i nā mīkina lima pale, nā maka aniani, a me nā maka i ka wā e hana ai; Hana i loko o kahi keʻena hoʻoheheʻe maikaʻi; Hōʻalo i ka hoʻopili ʻana me nā mea ʻokiʻekiʻe a me nā waikawa i ka wā e mālama ai. Inā hoʻopā wale ʻia a hoʻohu ʻia paha, pono e holoi ʻia a mālama ʻia me ka lāʻau lapaʻau i ka manawa.