(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER（CAS# 91229-91-3)

Hoʻolauna

ʻO ka di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate ka mea hoʻohuihui nona ke kinikini C14H23NO6. Eia ka wehewehe ʻana o nā waiwai, hoʻohana, hoʻomākaukau a me ka ʻike palekana o ka pūhui:

ʻAno:

-Nani: di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate he kala ʻole i ke keʻokeʻo crystalline paʻa.

-Solubility: Hiki ke hoʻoheheʻe ʻia i nā mea hoʻoheheʻe organik e like me ka ethanol, methanol a me dimethyl sulfoxide.

-Ka helu hoʻoheheʻe: hehee ka hui ma kahi o 104-105°C.

E hoʻohana:

ʻO ka di-tert-butyl (2S) -5-oxopyrrolidine-1,2-dicarboxylate he mea hoʻohana maʻamau i hoʻohana ʻia ma ke ʻano he reagent i ka synthesis organik. Hiki ke hoʻohana ʻia e synthesize i nā pūhui biologically active, e like me nā lāʻau lapaʻau a me nā mea polymer.

Hanana:

ʻO ka hoʻomākaukau ʻana i ka di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate e hana maʻamau ʻia e nā pae aʻe:

1. E hoʻonā i ka pyroglutamic acid tert-butyl ester i loko o ka dimethyl sulfoxide maloʻo.

2. Ua hoʻohui ʻia ka nui kūpono o ka N,N'-dihydroxyethyl isopropanamide a ua hoʻomaha ʻia ka hui ʻana ma lalo o 0°C.

3. Hoʻohui mālie i ka di-tert-butyl carbonate me ka mālama ʻana i ka mahana o ka hui ʻana ma lalo o 0°C.

4. Ma hope o ka pau ʻana o ka hopena, ua hoʻohui ʻia ka hui ʻana i ka wai e hoʻohua ai i kahi wai paʻa o di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate.

5. Ua loaʻa ka huahana hope ma nā ʻanuʻu o ka crystallization, kānana a me ka maloʻo.

ʻIke palekana:

di-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate pono e hoʻohana a mālama ʻia e like me nā hana palekana e pale aku ai i ka ʻili, nā maka a me ka inhalation. Eia kekahi, pono e mālama ʻia ma kahi maloʻo a maloʻo a mamao i ke ahi a me nā mea ʻona. No ka ʻike palekana, e nānā i ka Pepa ʻIkepili Palekana Kemika (MSDS) a i ʻole ka ʻike pili i hāʻawi ʻia e ka mea hoʻolako.