ʻO ka sodium nitroprusside dihydrate (CAS # 13755-38-9)

Nā Code Risk	R25 - He mea ʻawaʻawa inā ʻai ʻia R26/27/28 – He mea make loa ma ka inhalation, pili me ka ili a ina e moni ia.
Ka wehewehe palekana	S45 – Inā loaʻa ka pōʻino a i ʻole ka maikaʻi ʻole, e ʻimi koke i ka ʻōlelo aʻo kino (e hōʻike i ka lepili inā hiki.) S36/37/39 – E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka. S22 – Mai hanu i ka lepo.
UN ID	UN 3288 6.1/PG 3
WGK Kelemānia	3
RTECS	LJ8925000
NUI FLUKA BRAND F	3
TSCA	ʻAe
HS Code	28372000
Papa Hazard	6.1
Hui Pūʻulu	III
Kaʻawaʻawa	LD50 ma ka waha ma ka Lapi: 99 mg/kg

Kuhikuhi Hōʻike hou aku

1. Tian, ​​Ya-qin, et al. "ʻO ka hoʻohālikelike ʻana i nā ʻenehana unuhi ʻokoʻa a me ka hoʻonui ʻana i ka extrac kōkua microwave…

Hiki ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka waiʻona. ʻAʻole paʻa kona ʻano wai a hiki ke hoʻoheheʻe ʻia a lilo i ʻōmaʻomaʻo.

hoʻolauna	sodium nitroprusside (molecular formula: Na2[Fe(CN)5NO]· 2H2O, chemical name: sodium nitroferricyanide dihydrate) he vasodilator hana wikiwiki a pōkole, i hoʻohana ʻia no ka hypertension pilikia e like me ka hypertensive crisis, hypertensive encephalopathy, maʻi hypertension, paroxysmal hypertension ma mua a ma hope o ka hana pheochromocytoma, etc., hiki ke hoʻohana ʻia no ka hoʻomalu ʻia. hypotension i ka wā o ka hana anesthesia.
hopena	ʻO ka sodium nitroprusside he vasodilator wikiwiki wikiwiki, nona ka hopena dilation pololei ma nā ʻiʻo maʻemaʻe arterial a me ka venous, a e hōʻemi i ka pale ʻana o nā kīʻaha peripheral ma o ka hoʻonui ʻana i nā kīʻaha koko., E hana i ka hopena antihypertensive. Hiki i ka hoʻoheheʻe ʻana o ke koko ke hoʻemi i ka ukana ma mua a ma hope o ka puʻuwai, hoʻomaikaʻi i ka puka ʻana o ka naʻau, a hoʻemi i ka reflux koko ke pani ʻole ʻia ka valve, i hiki ke hoʻomaha ʻia nā hōʻailona o ka naʻau.
nā hōʻailona	1. ua hoʻohana 'ia no ka pilikia hypotension o hypertensive emergencies, e like me hypertensive pilikia, hypertensive encephalopathy, malignant hypertension, paroxysmal hypertension ma mua a ma hope o ka pheochromocytoma oki, a hiki no hoi ke hoohana no ka hoomaluia hypotension i ka surgical anesthesia. 2. No ka puʻuwai puʻuwai koʻikoʻi, me ka edema pulmonary acute. Hoʻohana ʻia ia no ka pau ʻole o ka naʻau i ka myocardial infarction a i ʻole ke pani ʻia ka valve (mitral a i ʻole aortic valve).
pharmacokinetics	hiki i ke koko kiʻekiʻe ma hope koke o ka intravenous drip, a hilinaʻi kona pae i ka hopena. Hoʻopili ʻia kēia huahana e nā koko ʻulaʻula i loko o ka cyanide, cyanide i loko o ke akepaʻa ua hoʻololi ʻia i thiocyanate, a ʻaʻohe hana vasodilating ka metabolite; Hiki i ka cyanide ke komo pū i ka metabolism o ka huaora B12. Hana koke kēia huahana ma hope o ka hoʻoponopono ʻana a hiki i ka piko o ka hana, a mālama ʻia no 1 ~ 10 mau minuke ma hope o ka pau ʻana o ka drip intravenous. ʻO ka hapalua o ke ola o nā mea maʻi me ka hana renal maʻamau he 7 mau lā (ana ʻia e ka thiocyanate), hoʻolōʻihi ʻia i ka wā ʻilihune o ka hana renal a i ʻole haʻahaʻa loa ka sodium koko, a hoʻokuʻu ʻia ia e ka puʻupaʻa.
He kaʻina hana synthetic no ka hoʻomākaukau ʻana	sodium nitroprusside, me nā ʻanuʻu aʻe: 1) Synthesizing copper nitroso ferrocyanide: hoʻohui i ka nui kūpono o ka wai i hoʻomaʻemaʻe ʻia e hoʻoheheʻe i ka potassium nitroso-ferricyanide i loko o kahi pahu crystallization, hoʻomehana i 70-80 ℃ e hoʻoheheʻe loa ia, a hoʻohui mālie i ka copper sulfate pentahydrate wai hāleʻa dropwise, ma hope o ka hopena ua malama ia mehana no 30 minuke, centrifuge, ka ʻO ka keke kānana centrifuged (copper nitroso ferricyanide) i hoʻokomo ʻia i loko o ka pahu crystallization. 2) Synthetic sodium nitroprusside (sodium nitronitroferricyanide): E hoʻomākaukau i ka sodium bicarbonate aqueous solution e like me ka ratio hānai, a hoʻokuʻu mālie i loko o ka nitroso ferricyanide ma 30-60 degrees C. Ma hope o ka hopena, centrifuge, hōʻiliʻili i ka filtrate a me ka wai. 3) Hoʻopili a me ka crystallization: ʻO ka kānana i hōʻiliʻili ʻia a me ka wai wai e hoʻomoʻi ʻia i loko o kahi pahu hoʻopaʻa haʻahaʻa, a hoʻohui mālie ʻia ka ʻakika acetic glacial a hiki i ka loaʻa ʻole o nā ʻōhū. E hoʻohuli i ka paila a me ka wela a hiki i ka 40-60 degrees C, e hoʻomaka i ka noʻonoʻo ʻana, e noʻonoʻo i ka nui o ka ua crystals, e pani i ka pahu mahu, e hoʻomākaukau ai no ka crystallization. 4) Hoʻomaloʻo Centrifugal: ma hope o ka crystallization, hoʻoneʻe ʻia ka supernatant, hoʻoulu ʻia nā kristal a me ka centrifuged, waiho ʻia ka keke kānana i loko o kahi pā kila kila, a loaʻa ka huahana ma ka maloʻo maloʻo.
hana olaola	ʻO ka sodium Nitroprusside kahi vasodilator ikaika e hana ma ka hoʻokuʻu wale ʻana i NO i loko o ke koko.
Kuhikuhi	Waiwai
Hoʻohana	Hoʻohana ʻia e like me ka reagent no ka hoʻoholo ʻana i nā aldehydes, ketones, sulfides, zinc, sulfur dioxide, etc. Hoʻohana ʻia e like me ka reagent no ka hoʻoholo ʻana i nā aldehydes, acetone, sulfur dioxide, zinc, Alkali metala, sulfides, etc. ʻO nā lāʻau lapaʻau. Ka hōʻoia ʻana o nā aldehydes a me nā ketones, zinc, sulfur dioxide a me alkali metala sulfides. ʻIkepili Chromatic, hōʻike mimi.